1086610-84-5

Basic information

• Product Name: 7-({2-chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)-2,3-dihydro-1H-isoindol-1-one
• Synonyms: 7-({2-chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)-2,3-dihydro-1H-isoindol-1-one
• CAS NO: 1086610-84-5
• Molecular Weight: 453.909
• Mol File: 1086610-84-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-({2-chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)-2,3-dihydro-1H-isoindol-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-({2-chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)-2,3-dihydro-1H-isoindol-1-one(1086610-84-5)
• EPA Substance Registry System: 7-({2-chloro-7-[(4-methylphenyl)sulfonyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino)-2,3-dihydro-1H-isoindol-1-one(1086610-84-5)

Safety Data

• Hazardous Substances Data: 1086610-84-5(Hazardous Substances Data)

Upstream product

• 169044-98-8 7-amino-2,3-dihydro-1H-isoindol-1-one 
• 934524-10-4 2,4-dichloro-7-p-methylbenzenesulfonyl-7H-pyrrole[2,3-d]pyrimidin-4-amine 

Relevant articles and documents

Reversible carboxamide-mediated internal activation at C(6) of 2-chloro-4-anilino-1H-pyrrolo[2,3-d]pyrimidines

(Chemical Equation Presented) A synthetic route to bisanilino-1H-pyrrolo[2, 3-d]pyrimidines has been discovered, wherein the C(6)-chloride reactivity is necessarily enhanced via reversible acid-catalyzed internal activation of the pyrimidine ring by a C(1′)-carboxamide moiety. Subsequent selective nucleophilic displacements at C(6) and C(1′) constitute a one-pot tandem protocol for the rapid assembly of bisanilino-1H-pyrrolo[2,3-d]pyrimidines.