108734-55-0Relevant articles and documents
Chiral auxiliary-mediated enantioenrichment of (±)-ibuprofen, under steglich conditions, with secondary alcohols derived from (R)-carvone
Amongero, Marcela,Visnovezky, Damian,Kaufman, Teodoro S.
experimental part, p. 1017 - 1036 (2010/10/21)
The synthesis of a series of chiral secondary alcohols derived from (R)-carvone, and the stereochemical outcome of their reaction with (±)-ibuprofen, is reported. The racemic drug was transformed into the corresponding diastereomeric esters mediated by DC