1089051-56-8 Usage
Description
trans/cis Resveratrol-D4, also known as Resveratrol-D4 (R150000), is a labeled compound found in wine and is a minor constituent. It is a polyphenolic phytoalexin that occurs in various plants, including grapes, and possesses anti-inflammatory, antioxidant, and anticancer properties. trans-Resveratrol-D4 is used as an internal standard for the quantification of trans-resveratrol by GCor LC-MS.
Uses
Used in Pharmaceutical Industry:
trans/cis Resveratrol-D4 is used as an internal standard for the quantification of trans-resveratrol by GCor LC-MS for accurate measurement and analysis of the compound in various pharmaceutical applications.
Used in Anti-inflammatory Applications:
trans/cis Resveratrol-D4 is used as an anti-inflammatory agent, as it inhibits the cyclooxygenase and hydroperoxidase activities of COX-1, which are involved in inflammation.
Used in Antioxidant Applications:
trans/cis Resveratrol-D4 is used as an antioxidant, as it inhibits free radical formation in cells, protecting them from oxidative stress and damage.
Used in Anticancer Applications:
trans/cis Resveratrol-D4 is used as an anticancer agent, as it has been shown to inhibit events associated with tumor initiation, promotion, and progression. It reduces the incidence and number of tumors in various cancer models and activates sirtuin 1 (SIRT1), which is involved in regulating cellular processes related to aging and cancer.
Used in Research and Development:
trans/cis Resveratrol-D4 is used as a research tool in the development of new drugs and therapies, as it inhibits a variety of targets, including ERK1, JNK1, Src, PKCα, aromatase/CYP19, and DNA polymerases α and δ, which are involved in various cellular processes and diseases.
Used in Lifespan Extension Studies:
trans/cis Resveratrol-D4 is used in studies to understand its potential to prolong lifespan in model organisms, such as C. elegans, D. melanogaster, and mice, which can provide insights into aging and age-related diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 1089051-56-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,8,9,0,5 and 1 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1089051-56:
(9*1)+(8*0)+(7*8)+(6*9)+(5*0)+(4*5)+(3*1)+(2*5)+(1*6)=158
158 % 10 = 8
So 1089051-56-8 is a valid CAS Registry Number.
1089051-56-8Relevant articles and documents
trans-resveratrol-d4, a molecular tracer of the wild-type phytoalexin; synthesis and spectroscopic properties
Gabriele, Bartolo,Benabdelkamel, Hicham,Plastina, Pierluigi,Fazio, Alessia,Sindona, Giovanni,Di Donna, Leonardo
, p. 2953 - 2956 (2008)
A convenient, six-step synthesis of the so far unknown trans-resveratrol- d4, (E)-3′,4,5′-trihydroxy-2,3,5,6-tetradeuterostilbene, starting from commercially available phenol-d6, with an overall yield of 25%, is described. The final
