108980-49-0

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 7-methoxy-2-(4-methylphenyl)-
• CAS NO: 108980-49-0
• Molecular Formula: C17H14O3
• Molecular Weight: 266.296
• Mol File: 108980-49-0.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 7-methoxy-2-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 7-methoxy-2-(4-methylphenyl)-(108980-49-0)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 7-methoxy-2-(4-methylphenyl)-(108980-49-0)

Safety Data

• Hazardous Substances Data: 108980-49-0(Hazardous Substances Data)

Upstream product

• 137109-37-6 (E)-1-(2-hydroxy-4-methoxyphenyl)-3-p-tolylprop-2-en-1-one 
• 496784-98-6 1-(2-hydroxy-4-methoxyphenyl)-3-(4-methylphenyl)-1,3-propanedione 
• 849367-91-5 4-methylbenzoic acid 2'-acetyl-5'-methoxyphenyl ester 
• 552-41-0 1-(2-hydroxy-4-methoxyphenyl)ethanone 
• 874-60-2 4-methyl-benzoyl chloride 
• 673-22-3 2-Hydroxy-4-methoxybenzaldehyde 
• 60512-56-3 1-(2,2-dibromovinyl)-4-methylbenzene 
• 19202-27-8 2-acetoxy-4-methoxy-benzoyl chloride 
• 17336-11-7 2-acetoxy-4-methoxybenzoic acid 
• 1403475-71-7 5-methoxy-2-(3-p-tolylpropioloyl)phenyl acetate 
• 1376543-55-3 C₁₈H₁₈O₄ 
• 137109-37-6 1-(2-hydroxy-4-methoxyphenyl)-3-(p-tolyl)prop-2-en-1-one 
• 104-87-0 4-methyl-benzaldehyde 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 

Downstream Products

• 1371663-61-4 4-(2-hydroxy-4-methoxyphenyl)-6-(4-methylphenyl)-2-aminopyrimidine 
• 1219977-54-4 C₁₇H₁₄O₂S 
• 329727-22-2 2-(4-formylphenyl)-7-methoxy-4H-1-benzopyran-4-one 
• 78298-69-8 4'-Methyl-7-hydroxyflavone 

Relevant articles and documents

Rh-Catalyzed aldehydic C-H alkynylation and annulation

Novel Rh-catalyzed aldehydic C-H bond alkynylation and annulation for the in situ synthesis of chromones and aurones are described. It involves the sequential aldehyde C-H bond alkynylation of salicylaldehyde with in situ generated 1-bromoalkyne from 1,1-

Synthesis of 3-HCF2S-Chromones through Tandem Oxa-Michael Addition and Oxidative Difluoromethylthiolation

A simple protocol for the synthesis of difluoromethylthiolated chromen-4-ones using elemental sulfur and ClCF2CO2Na as the difluoromethylthiolating agent is described. Three-component reactions of 2′-hydroxychalcones, ClCF2CO2Na, and sulfur under basic conditions using TEMPO as the oxidant afforded HCF2S-containing 4H-chromen-4-one and 9H-thieno[3,2-b]chromen-9-one derivatives in good yield. The protocol is practical and efficient, and the starting materials are cheap and readily available.

Pd(OAc)2/S=PPh3 accelerated activation of gem-dichloroalkenes for the construction of 3-arylchromones

The Pd-catalyzed regioselective intramolecular nucleophilic substitution of gem-dichloroalkene derivatives with salicylaldehydes leading to the synthesis of 3-arylchromones has been developed. Pd(OAc)2/S=PPh3 could activate gem-dichloroalkenes and undergo nucleophilic substitution by salicylaldehydes with the aid of a base.