109-63-7 Usage
Chemical Description
Different sources of media describe the Chemical Description of 109-63-7 differently. You can refer to the following data:
1. Boron trifluoride etherate is a Lewis acid that is commonly used as a catalyst in organic synthesis.
2. Boron trifluoride etherate is a Lewis acid used as a catalyst in organic synthesis.
3. Boron trifluoride etherate is a Lewis acid catalyst used to obtain 1-(p_nitrophenyl)cyclopentane carboxaldehyde.
Chemical Properties
Different sources of media describe the Chemical Properties of 109-63-7 differently. You can refer to the following data:
1. Colorless to brown fuming liquid.
2. Boron trifluoride etherates: (compounded with
methyl ether) is moisture-sensitive, corrosive, flammable liquid.
uses
Boron trifluoride diethyl etherate is used as a Lewis acid catalyst in Mukaiyama aldol addition, alkylation, acetylation, isomerization, dehydrations and condensation reactions. It is involved in the prepattion of polyethers in polymerization reactions. As a catalyst, it is used in the preparation of cyclopentyl- and cycloheptyl[b]indoles and other diborane. It is also used in sensitive neutron detectors in ionization chambers as well as monitoring radiation levels in earth?s atmosphere.
Preparation
Different sources of media describe the Preparation of 109-63-7 differently. You can refer to the following data:
1. Boron trifluoride gas, produced by heating the sulfuric acid, calcium fluoride (fluorite) and boric acid together, reacts with ether boron to produce the trifluoride etherate crude product, thus we can refine it to get the finished product. The consumption of raw material is as followed: boric acid (≥98%), 560kg/t; calcium fluoride(≥90%) 1150kg/t; fuming sulfuric acid (104.5%), 4100kg/t; ether(≥99%) 725kg/t.In absorption method shown in the chemical equations as followed, diethyl ether absorb boron trifluoride gas, produced by heating the sulfuric acid, calcium fluoride (fluorite) and boric acid together, to produce trifluoride etherate crude complex compound by vacuum distillation.3H2SO4+2H33BO3+3CaF2→2BF3+3CaSO4+6H2OBF3+(C2H5)2O→(C2H5)2O?BF3
2. Boron trifluoride etherate is prepared by the reaction of vapors of boron trifluoride with that of anhydrous diethyl ether:BF3 (g) + (C2H5)2O (g) → (C2H5)2O?BF3.
Toxicity
See boron trifluoride.
Physical properties
Fuming liquid; stable at ambient temperatures but hydrolyzed on exposure to moist air; density 1.125 g/mL; refractive index 1.348; solidifies at -60.4°C; boils at 125.7°C; flash point (open cup) 147°F (68.8°C); decomposes in water.
Uses
Catalyst in acetylation, alkylation, polymerization, dehydration, and condensation reactions.
Application
Catalyst in the synthesis of polyol chains. Reagent for the coupling of imines to allylstannanes and 4′-nitrobenzenesulfenanilide to alkenes and alkynes.Lewis acid reagent with broad applicationCatalyst used in the preparation of cyclopentyl- and cycloheptyl[b]indoles from aryl cyclopropyl ketones via [3+2] cycloaddition.
General Description
Boron trifluoride etherate is a fuming liquid. Boron trifluoride etherate may be corrosive to skin, eyes and mucous membranes. Boron trifluoride etherate may be toxic by inhalation. Upon exposure to water Boron trifluoride etherate may emit flammable and corrosive vapors. Boron trifluoride etherate is used as a catalyst in chemical reactions.
Air & Water Reactions
Highly flammable. Fuming liquid, immediately hydrolyzed by moisture in air to form hydrogen fluoride [Merck 11th ed. 1989].
Reactivity Profile
Boron trifluoride diethyl ether complex is a stable, highly flammable, colourless to brown fuming, corrosive liquid with a sharp pungent odour. It forms explosive peroxides in contact with air or oxygen. It reacts exothermically with water to form extremely flammable diethyl ether and toxic, corrosive boron trifluoride hydrates. The chemical is incompatible with bases, amines, and alkali metals. It immediately gets hydrolysed by moisture in air to form hydrogen fluoride. Boron trifluoride diethyl ether has applications in chemical laboratory as a catalyst in chemical reactions.
Hazard
The compound is highly toxic by inhalation. Skin contact causes burns.
Health Hazard
May cause toxic effects if inhaled or ingested/swallowed. Contact with substance may cause severe burns to skin and eyes. Fire will produce irritating, corrosive and/or toxic gases. Vapors may cause dizziness or suffocation. Runoff from fire control or dilution water may cause pollution.
Fire Hazard
Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Flammability and Explosibility
Flammable
Potential Exposure
Used as a catalyst.
Shipping
Diethyl: UN2604 Boron trifluoride diethyl
etherate, Hazard class: 8; Labels: 8—Corrosive material,
3—Flammable liquid. Dimethyl: UN2965 Boron trifluoride
dimethyl etherate, Hazard class: 4.3; Labels: 4.3—
Dangerous when wet, 8—Corrosive material, 3—
Flammable liquid.
Incompatibilities
Reacts with air forming corrosive hydrogen
fluoride vapors. Incompatible with oxidizers (may
cause fire and explosion), water, steam or heat, forming
corrosive and flammable vapors. Peroxide containing etherate
reacts explosively with aluminum lithium hydride,
magnesium tetrahydroaluminate. Mixtures with phenol
react explosively with 1,3-butadiene. Presumed to form
explosive peroxides.
Check Digit Verification of cas no
The CAS Registry Mumber 109-63-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,0 and 9 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 109-63:
(5*1)+(4*0)+(3*9)+(2*6)+(1*3)=47
47 % 10 = 7
So 109-63-7 is a valid CAS Registry Number.
InChI:InChI:1S/C4H10BF3O/c1-3-9(4-2)5(6,7)8/h3-4H2,1-2H3
109-63-7Relevant articles and documents
-
Seel
, p. 331,349 (1943)
-
Synthesis and reactivity studies of dicationic dihydrogen complexes bearing sulfur-donor ligands: A combined experimental and computational study
Gandhi, Thirumanavelan,Rajkumar, Subramani,Prathyusha,Priyakumar, U. Deva
, p. 1434 - 1443 (2013/05/22)
A series of dihydrogen complexes trans-[Ru(η2-H 2){SC(SR)H}(dppe)2][X][BF4] (R = CH 3, X = OTf; R = C6H5CH2, X = BPh4; R = H2C=CHCH2, X = BPh4; dppe = Ph2PCH2CH2PPh2) bearing sulfur-donor ligands has been synthesized by protonation of the (alkyl dithioformate)hydrido complexes trans-[Ru(H){SC(SR)H}(dppe)2][X] by using HBF4·Et2O. Competitive substitution reactions between H2 and SC(SR)H in trans-[Ru(η2-H 2){SC(SR)H}(dppe)2][X][BF4] have been studied by treatment with CH3CN, CO, and P(OCH3)3. These resulted in the expulsion of SC(SR)H from the metal center, thus indicating that the alkyl dithioformate ligand is more labile than H 2. Bonding of alkyl dithioformate ligands (sulfur-donor ligands) trans to H2 have been studied by comparing the H-H distances and chemical-shift values (1H NMR spectroscopy) of the various dihydrogen complexes bearing different trans ligands. This study qualitatively suggests that the alkyl dithioformate ligands in these trans-dihydrogen complexes show a poor π effect, and it is further supported by density functional theory calculations. The first example of a dihydrogen complex bearing dithioformic acid, trans-[Ru(η2-H2){SC(SH)H}(dppe) 2][BF4]2, was obtained by protonation of trans-[Ru(H){SC(S)H}(dppe)2] by using HBF4·Et 2O. Copyright
Syntheses, structures, and reactivity studies of half-open ruthenocenes and their oxodienyl analogues
Navarro Clemente, M. Elena,Saavedra, Patricia Juárez,Vásquez, Marisol Cervantes,Angeles Paz-Sandoval,Arif, Atta M.,Ernst, Richard D.
, p. 592 - 605 (2008/10/08)
Improved synthetic routes to Cp*Ru(Pdl) complexes (Pdl = 2,4-dimethylpentadienyl and various oxodienyl ligands) including Cp*Ru(η5-2,4-Me2-C4 H3O) (1), Cp*Ru[η5-2,4-(t-Bu)2-C4 H3O] (1'), and Cp*ru(η5-2,4-Me2-C5 H5) (1″) were developed. When chelating, diphosphines were used as coligands and reactions with O2, Cl2 or H2 led to oxidative addition. A carbon-carbon bond activation was reported.