1093-96-5 Usage
General Description
Dansylsarcosine, also known as Dns-Sarcosine, is a fluorescent compound that is commonly used in biochemistry and clinical chemistry studies as a substrate for measuring the activity of transporter proteins such as organic anion transporters and organic anion-transporting polypeptides. It is a derivative of sarcosine, a non-proteinogenic amino acid, which is conjugated with the fluorescent dye dansyl to facilitate its detection and measurement. Dansylsarcosine is widely utilized in research to study the function and regulation of various transporter proteins, particularly those involved in the transport of organic anions across cell membranes, and it has also been investigated as a potential biomarker for various diseases and conditions related to transporter dysfunction. Additionally, dansylsarcosine is used as a standard compound for chromatographic analysis and as a reference material in analytical chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1093-96-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,9 and 3 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1093-96:
(6*1)+(5*0)+(4*9)+(3*3)+(2*9)+(1*6)=75
75 % 10 = 5
So 1093-96-5 is a valid CAS Registry Number.
InChI:InChI=1/C15H18N2O4S/c1-16(2)13-8-4-7-12-11(13)6-5-9-14(12)22(20,21)17(3)10-15(18)19/h4-9H,10H2,1-3H3,(H,18,19)
1093-96-5Relevant articles and documents
A fluorescent probe for butyrylcholinesterase activity in human serum based on a fluorophore with specific binding affinity for human serum albumin
Han, Min Su,Yoo, Soyeon
supporting information, p. 14574 - 14577 (2019/12/11)
Non-specific binding of a fluorescent probe to human serum albumin is problematic because it induces signal interference when the probe detects the target biomarker in human serum. To eliminate this problem, we used intrinsically problematic non-specific fluorescence in designing a fluorescent probe for butyrylcholinesterase activity in serum. The probe containing a fluorophore with specific binding affinity for albumin could sensitively detect butyrylcholinesterase activity in serum with high selectivity to acetylcholinesterase and screen the efficiency of butyrylcholinesterase inhibitors.
