109341-49-3Relevant articles and documents
A convenient synthesis of Benz[f]Indene
Ghorai, Sujit K.,Hazra, Nirmal K.,Mal, Dipakranjan
, p. 689 - 690 (1998)
The crucial annulation of sulfone aldehyde 2 with enone 3 has led to an operationally simple two-step synthesis of benz[f]indene1, and its derivatives 8 and 9 involving a new rearrangement.
Convenient synthesis of NCS - Chromophore metabolite isosteres: Binding agents for bulged DNA microenvironments
Lin, Yiqing,Jones, Graham B.,Hwang, Geum-Sook,Kappen, Lizzy,Goldberg, Irving H.
, p. 71 - 74 (2005)
(Chemical Equation Presented) A designed molecule with capacity to bind DNA bulges (20) has been prepared from readily available starting materials. The spirocyclic template was modeled on a metabolite of neocarzinostatin chromophore (NCSi-gb) and is equi
Synthesis and DNA binding of spirocyclic model compounds related to the neocarzinostatin chromophore.
Xi,Jones,Qabaja,Wright,Johnson,Goldberg
, p. 1375 - 1377 (1999)
[formula: see text] Spirocyclic model compounds which mimic the molecular architecture of one of the decomposition products of the antitumor agent NCS-chrom have been synthesized. These readily accessible molecules bind with remarkable efficiency to bulged DNA oligonucleotides, offering potential for the design of therapeutic agents.
Ortho-quinodimethane from anthracene epidioxide: Scope of the Diels-Alder reaction and mild preparation of naphthalene derivatives
Siret, Bernard,Albrecht, Sébastien,Defoin, Albert
, p. 1075 - 1079 (2015/01/08)
The thermal isomerisation of anthracene epidioxide 3 has been known to give phenylenedioxy-ortho-quinodimethane 5 as a reactive transient. We presented herein the scope of the Diels-Alder reaction of this transient 5 with some dienophiles. In addition, a mild synthesis of naphthalene derivatives has been developed via base-induced cleavage of the obtained Diels-Alder adducts.
Photochemical generation and reversible cycloaromatization of a nine-membered ring cyclic enediyne
Pandithavidana, Dinesh R.,Poloukhtine, Andrei,Popik, Vladimir V.
supporting information; experimental part, p. 351 - 356 (2009/06/18)
Irradiation of the nine-membered ring enediyne precursor, which has one of its triple bonds masked as cyclopropenone, efficiently(φ = 0.34) generates the reactive 4,5-benzocyclonona-2,6-diynol. The latter rapidly equilibrates with the corresponding 1,4-didehydronaphthalene diradical and then undergoes rate- limiting hydrogen abstraction to produce the ultimate product of the Bergman cyclization, benz[f]indanol.