1093956-69-4

Basic information

• Product Name: 1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate
• Synonyms: 1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate
• CAS NO: 1093956-69-4
• Molecular Weight: 338.809
• Mol File: 1093956-69-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate(1093956-69-4)
• EPA Substance Registry System: 1,1-dimethylethyl 4-(4-chloro-2-fluorophenyl)-4-cyano-1-piperidinecarboxylate(1093956-69-4)

Safety Data

• Hazardous Substances Data: 1093956-69-4(Hazardous Substances Data)

Upstream product

• 75279-53-7 2-(4-chloro-2-fluoro-phenyl)acetonitrile 
• 118753-70-1 N-(tert-butyloxycarbonyl)bis(2-chloroethyl)amine 

Downstream Products

• 1150315-75-5 4-(4-chloro-2-fluorophenyl)-4-piperidinecarboxylic acid 
• 1093956-71-8 C₁₂H₁₂ClFN₂ 
• 1228538-16-6 4-(4-chloro-2-fluorophenyl)-4-piperidinecarbonitrile hydrochloride 

Relevant articles and documents

METHOD FOR PREPARING A SPIROINDOLINE AND A PRECURSOR THEREOF

The present invention relates to a method comprising the step of contacting a protected N,N-bis(2-X-ethyl)amine with a (2-fluorophenyl)acetonitrile in the presence of a water- soluble phase transfer reagent, concentrated aqueous base, and an immiscible organic solvent, and under such conditions to form a 4-(2-fluorophenyl)-4-piperidinecarbonitrile in at least a 70% yield, wherein X is a leaving group. The 4-(2-fluorophenyl)-4- piperidinecarbonitrile is useful in preparing spiroindolines, which can be used as precursors of compounds that are modulators of CCR2 receptor.

INDOLINYL-, BENZOFURANYL-, AND BENZOTHIENYL- AMIDES AS MODULATORS OF CHEMOKINE RECEPTORS

The present invention relates to a compound of formula (I): or a pharmaceutically acceptable salt thereof; wherein R1-R5, X, Y, m, and n are as defined herein. Compounds of the present invention are useful for the treatment of a vari

SPIROINDOLINES AS MODULATORS OF CHEMOKINE RECEPTORS

The present invention relates to a compound of the following formula: where R1-R6, R10, Y, n, m, p, and q are as defined herein. Compounds and compositions of the present invention are useful for the treatment of diseases