109403-64-7

Basic information

• Product Name: N-(2-Furanylmethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine
• Synonyms: Furfuryl tetrahydropyranyladenine;N-(2-Furanylmethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine
• CAS NO: 109403-64-7
• Molecular Formula: C₁₅H₁₇N₅O₂
• Molecular Weight: 299.32778
• Mol File: 109403-64-7.mol
• Article Data: 5

Chemical Properties

• Melting Point: 138-139℃
• Boiling Point: 526.4±60.0 °C(Predicted)
• Appearance: /
• Density: 1.47
• PKA: 3.01±0.10(Predicted)
• CAS DataBase Reference: N-(2-Furanylmethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-Furanylmethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine(109403-64-7)
• EPA Substance Registry System: N-(2-Furanylmethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine(109403-64-7)

Safety Data

• Hazardous Substances Data: 109403-64-7(Hazardous Substances Data)

Usage

General Description

N-(2-Furanylmethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine is a chemical compound with a purine structure, containing a furanyl group and a tetrahydro-2H-pyran-2-yl group. It is also known as 2-Furanyl-N-(tetrahydro-2H-pyran-2-yl)adenine and is a derivative of adenine, a nucleobase found in DNA and RNA. N-(2-Furanylmethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine is a purine analog and may have potential biological activity, particularly in the context of anti-inflammatory or anti-cancer properties. Its specific molecular structure suggests that it may interact with biological molecules in a unique way, impacting cellular processes or signaling pathways. Further research is needed to fully understand the potential uses and effects of N-(2-Furanylmethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine.

Upstream product

• 617-89-0 furan-2-ylmethanamine 
• 7306-68-5 6-chloro-9-(tetrahydro-2H-pyran-2-yl)-9H-purine 
• 110-87-2 3,4-dihydro-2H-pyran 
• 87-42-3 6-chloro-7H-purine 
• 525-79-1 6-furfurylaminopurine 
• 50-66-8 6-methylthiopurine 
• 19769-32-5 6-methylsulfonylpurine 
• 525-79-1 kinetin 

Relevant articles and documents

X-ray structure, NMR and stability-in-solution study of 6-(furfurylamino)-9-(tetrahydropyran-2-yl)purine - A new active compound for cosmetology

The crystal and molecular structure of 6-(furfurylamino)-9-(tetrahydropyran-2-yl)purine (1) was determined at 150(2) K. The compound crystallizes in monoclinic P21/c space group with a = 10.5642(2), b = 13.6174(3), c = 10.3742(2) ?, V = 1460.78(5) ?3, Z = 4, R(F) = for 3344 unique reflections. The purine moiety and furfuryl ring are planar and the tetrahydropyran-2-yl is disordered in the ratio 1:3, probably due to the chiral carbon atom C(17). The individual 1H and 13C NMR signals were assigned by 2D correlation experiments such as 1H-1H COSY and ge-2D HSQC. Stability-in-solution was determined in methanol/water in acidic pH (3-7).

6,8-DISUBSTITUTED-9-(HETEROCYCLYL)PURINES, COMPOSITIONS CONTAINING THESE DERIVATIVES AND THEIR USE IN COSMETIC AND MEDICINAL APPLICATIONS

6,8-Disubstituted-9-(heterocyclyl) purines which can be used in pharmaceutical and cosmetic compositions and/or applications are provided. These 6,8-disubstituted-9-(heterocyclyl) purines have a wide range of biological activities, including for example antioxidant, anti-inflammatory, anti-senescent, as well as well as other activities which are especially useful in pharmaceutical and cosmetic applications.

Synthesis of 6-alkyl- and arylamino-9-(tetrahydro-2-pyranyl)purines via 6-methylsulfonylpurine

A series of six potential plant hormones, 6-alky- and arylamino-9- (tetrahydro-2-pyranyl)purines were prepared in three steps in 35 to 45% overall yield from 6-methylthiopurine via 6-methylsulfonylpurine.