109559-14-0

Basic information

• Product Name: 1-benzyl-3-(R)-benzyl piperazine-2,5-dione
• Synonyms: 1-benzyl-3-(R)-benzyl piperazine-2,5-dione
• CAS NO: 109559-14-0
• Molecular Weight: 294.353
• Mol File: 109559-14-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-benzyl-3-(R)-benzyl piperazine-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-3-(R)-benzyl piperazine-2,5-dione(109559-14-0)
• EPA Substance Registry System: 1-benzyl-3-(R)-benzyl piperazine-2,5-dione(109559-14-0)

Safety Data

• Hazardous Substances Data: 109559-14-0(Hazardous Substances Data)

Upstream product

• 5619-07-8 methyl 2-amino-3-phenylpropanoate hydrochloride 
• 76315-01-0 N-benzyl-N-(tert-butoxycarbonyl)glycine 
• 7628-28-6 N-(N-benzyl-glycyl)-phenylalanine 
• 98-95-3 nitrobenzene 

Downstream Products

• 1060719-93-8 (+/-)-1-[2'-(benzyl)piperazin-1'-yl]isoquinoline 
• 1060720-13-9 (+/-)-1-[2',4'-(dibenzyl)piperazin-1'-yl]isoquinoline 
• 179051-52-6 1-benzyl-3(S)-benzylpiperazine 

Relevant articles and documents

1-[(2'-SUBSTITUTED)-PIPERAZIN-1'-YL]-ISOQUINOLINES AS NOREPINEPHRINE TRANSPORTER INHIBITOR THERAPEUTICS AND POSITRON EMISSION TOMOGRAPHY IMAGING AGENTS

Racemic mixtures and enantiomerically pure forms of novel 1-[(2'- substituted)-piperazin-1'-yl]-isoquinolines are norepinephrine (NE) transporter (NET) inhibitor compounds. Compounds of the invention are considered therapeutic agents for central nervous s

Aminoheterocyclic derivatives as antithrombotic or anticoagulant

The invention concerns compounds of formula (I), wherein each of G1, G2 and G6 is CH or n; m is 1 or 2; R1 includes hydrogen, halogeno and (1-4C)alkyl; M1 is a group of formula: NR2 -L1 -T1 R3, in which R2 and R3 together form a (1-4C)alkylene group, L1 includes (1-4C)alkylene, and T1 is CH or N; A may be a direct link; M2 is a group of the formula: (T2 R4)r -L2 T3 R5 in which R is 0 or 1, each of T2 and T3 is CH or N, each of R4 and R5 is hydrogen or (1-4C)alkyl, or R4 and R5 together form a (1-4C)alkylene group, and L2 includes (1-4C)alkylene; M3 may be a direct link to X; X includes sulphonyl; and Q includes naphthyl and a heterocycle moiety; or a pharmaceutically-acceptable salt thereof; processes for their preparation, pharmaceutical compositions containing them and their use as antithrombotic or anticoagulant agents.