109741-24-4

Basic information

• Product Name: ApovincaMinic Acid Ethyl Ester N-Oxide
• Synonyms: ApovincaMinic Acid Ethyl Ester N-Oxide;(41S,13aS)-12-(ethoxycarbonyl)-13a-ethyl-2,3,41,5,6,13a-hexahydroindolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine 4(1H)-oxide;(3α,16α)-Eburnamenine-14-carboxylic Acid Ethyl Ester 4-Oxide;Vinpocetine Impurity H
• CAS NO: 109741-24-4
• Molecular Formula: C22H26N2O3
• Molecular Weight: 366.45344
• Mol File: 109741-24-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: Benzene (Slightly), Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: ApovincaMinic Acid Ethyl Ester N-Oxide(CAS DataBase Reference)
• NIST Chemistry Reference: ApovincaMinic Acid Ethyl Ester N-Oxide(109741-24-4)
• EPA Substance Registry System: ApovincaMinic Acid Ethyl Ester N-Oxide(109741-24-4)

Safety Data

• Hazardous Substances Data: 109741-24-4(Hazardous Substances Data)

Usage

Uses

Apovincaminic Acid Ethyl Ester N-Oxide is an metabolite of Vinpocetine (V332502), a vasodilator cerebral.

Upstream product

• 42971-09-5 Vinpocetine 

Relevant articles and documents

Synthesis of vinca alkaloids and related compounds XXXVIII. Formation of dimers under Polonovski reaction conditions

The dimeric products (1a-c) have ben prepared by treatment of N-oxides derived from some indole alkaloids.Their structures have been elucidated by detailed NMR investigations and the structure of 1c determined by X-ray analysis.The importance of the E2-type trans-axial elimination of the N-acyloxy intermediate in the dimer formation has also been established.The iminium salts 4a-b and the derived pseudocyanide 6 have been prepared.