110109-68-7Relevant articles and documents
TiCl4 promoted reaction of aldehydes with 1,5-dienyl allylsilanes: Addition accompanied by cyclization
Vidari, Giovanni,Bonicelli, Maria Pia,Anastasia, Luigi,Zanoni, Giuseppe
, p. 3471 - 3474 (2000)
TICl4 readily promotes the addition of 1,5-dienyl allylsilanes to aliphatic aldehydes with concomitant cyclization to afford 1,3-cis- disubstituted methylenecyclohexanes with remarkable stereoselectivity. The trimethylsilyl group exerts a strong activating and directing influence on the regioselectivity and stereoselectivity of this biomimetic cyclization. (C) 2000 Elsevier Science Ltd.