110270-49-0

Basic information

• Product Name: 1,3-Propanediol, 2-(phenylmethyl)-, monoacetate, (R)-
• CAS NO: 110270-49-0
• Molecular Formula: C12H16O3
• Molecular Weight: 208.257
• Mol File: 110270-49-0.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: 1,3-Propanediol, 2-(phenylmethyl)-, monoacetate, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Propanediol, 2-(phenylmethyl)-, monoacetate, (R)-(110270-49-0)
• EPA Substance Registry System: 1,3-Propanediol, 2-(phenylmethyl)-, monoacetate, (R)-(110270-49-0)

Safety Data

• Hazardous Substances Data: 110270-49-0(Hazardous Substances Data)

Upstream product

• 110230-64-3 (R)-3-Acetoxy-2-benzylpropanol acetate 
• 2612-30-8 2-benzyl-1,3-propanediol 
• 108-24-7 acetic anhydride 
• 100-44-7 benzyl chloride 
• 100-39-0 benzyl bromide 
• 49769-78-0 2-benzyl-malonic acid dimethyl ester 
• 607-81-8 diethyl 2-benzylmalonate 
• 108-05-4 vinyl acetate 

Downstream Products

• 853793-50-7 Acetic acid (R)-2-phenoxymethyl-3-phenyl-propyl ester 
• 205380-74-1 (S)-2-benzyl-3-hydroxypropoxy tert-butyl dimethyl silane 
• 913546-09-5 (S)-2-benzyl-3-((tert-butyldimethylsilyl)oxy)propanal 
• 1357622-73-1 C₂₇H₄₄N₂O₆Si 
• 1357622-51-5 (S)-2-benzyl-1-(tert-butyl)dimethylsilyloxy-3-isocyanopropane 
• 1357622-49-1 (S)-2-benzyl-3-(tert-butyl)dimethylsilyloxy-1-formylaminopropane 
• 1357622-47-9 (S)-1-azido-2-benzyl-3-(tert-butyl)dimethylsilyloxypropane 
• 1357623-25-6 C₁₆H₂₉NOSi 
• 1374335-22-4 C₁₇H₃₀O₄SSi 
• 1224594-28-8 2R-phenyl-3-benzyloxypropyl acetate 
• 121232-85-7 (S)-(+)-2-(acetoxymethyl)-3-phenylpropanoic acid 
• 201999-26-0 (S)-2-benzyl-3-methanesulfonyloxy-1-propanol 
• 128349-90-6 (S)-2-Methoxymethoxymethyl-3-phenyl-propan-1-ol 
• 123802-80-2 (R)-2-hydroxymethyl-3-phenylpropionic acid 

Relevant articles and documents

Chemo- and Enzyme-Catalyzed Reactions Revealing a Common Temperature-Dependent Dynamic Solvent Effect on Enantioselectivity

The enantiomeric ratio E of enzyme-catalyzed (Candida antarctica lipase and lipase PS) and chemocatalyzed (L-proline-based diamines) acylation reactions of 1-(naphthalen-2-yl)ethanol, 2-phenylpropanol, and 2-benzylpropane-1,3-diol is dependent on solvent and temperature. Plots of In E vs. 1/T showed the presence of inversion temperatures (Tinv). The Tinv values for the bio-catalyzed and the chemo-catalyzed reactions are fairly in agreement, and correspond as well to the TNMR values obtained by variable-temperature 13C-NMR experiments on the substrates in the same solvent of the resolution. This result demonstrates that clustering effects in the substrate solvation manage the chemical and the enzymatic enantioselectivity, and, moreover, that the solute-solvent cluster is always the real reacting species in solution for chemical as well as for enzymatic reactions.

Design, asymmetric synthesis, and evaluation of pseudosymmetric sulfoximine inhibitors against HIV-1 protease

The HIV-1 protease is a validated drug target for the design of antiretroviral drugs to combat AIDS. We previously established the sulfoximine functionality as a valid transition state mimetic (TSM) in the HIV-1 protease inhibitors (PI) design and have id

Asymmetric synthesis of homoisoflavanone using lipase-catalyzed reaction

The (R)- and (S)-enantiomers of 3-benzyl-4-chromanone (homoisoflavanone) were synthesized starting with the optically active 2-benzyl-1,3-propanediol monoacetates, which were obtained via the lipase-catalyzed enantioselective reaction.