1103963-53-6Relevant articles and documents
Total synthesis of thuggacin B
Bock, Martin,Dehn, Richard,Kirschning, Andreas
, p. 9134 - 9137 (2008)
Final proof of the complete structures of thuggacins A-C was gained by a highly convergent and flexible total synthesis. Notable features include a substrate-controlled, titanium-mediated aldol reaction, a cross-metathesis approach for converting terminal alkenes into the corresponding vinyl iodides, and the cross-coupling of a complex vinyl iodide and terminal alkyne in the Sonogashira reaction. (Chemical Equation Presented).