110928-45-5

Basic information

• Product Name: Cyclohexanecarboxylic acid, 4-(hydroxymethyl)-, methyl ester, cis-
• CAS NO: 110928-45-5
• Molecular Formula: C9H16O3
• Molecular Weight: 172.224
• Mol File: 110928-45-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Cyclohexanecarboxylic acid, 4-(hydroxymethyl)-, methyl ester, cis-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarboxylic acid, 4-(hydroxymethyl)-, methyl ester, cis-(110928-45-5)
• EPA Substance Registry System: Cyclohexanecarboxylic acid, 4-(hydroxymethyl)-, methyl ester, cis-(110928-45-5)

Safety Data

• Hazardous Substances Data: 110928-45-5(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 73094-35-6 trans-4-(hydroxymethyl)cyclohexane-1-carboxylic acid 
• 1011-85-4 (1S,4S)-4-(methoxycarbonyl)cyclohexane-1-carboxylic acid 

Relevant articles and documents

STAT DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

NK1 RECEPTOR ANTAGONIST

A problem of the present invention is to provide a new compound which has NK1 receptor antagonist activity, and thus is useful for the prevention or treatment of cancer-chemotherapy-induced nausea and vomiting. A compound represented by the formula (I): wherein W represents a fluorine atom and the like, ring A represents a cycloalkyl and the like, X1 represents CH or N, R represents methyl and the like, Y represents 0 to 2, U1, U2 and U3 each independently represents a single bond and the like, or a pharmaceutically acceptable salt thereof. The compounds of the present invention or pharmaceutically acceptable salts thereof have an excellent NK1 receptor antagonist activity, and thus are also useful as an agent for the prevention or treatment of cancer-chemotherapy-induced nausea and vomiting.