111-73-9

Basic information

• Product Name: 4-ethoxybutan-1-ol
• Synonyms: 4-ethoxybutan-1-ol;1-Butanol, 4-ethoxy-;BRN 1732976;4-Ethoxy-1-butanol
• CAS NO: 111-73-9
• Molecular Formula: C₆H₁₄O₂
• Molecular Weight: 118.17416
• EINECS: 203-901-9
• Mol File: 111-73-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 183.2°Cat760mmHg
• Flash Point: 56.9°C
• Appearance: /
• Density: 0.899g/cm³
• Vapor Pressure: 0.224mmHg at 25°C
• Refractive Index: 1.418
• PKA: 15.08±0.10(Predicted)
• CAS DataBase Reference: 4-ethoxybutan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ethoxybutan-1-ol(111-73-9)
• EPA Substance Registry System: 4-ethoxybutan-1-ol(111-73-9)

Safety Data

• Hazardous Substances Data: 111-73-9(Hazardous Substances Data)

Usage

General Description

4-ethoxybutan-1-ol, also known as butyl ethyl ether, is a chemical compound with the molecular formula C6H14O and a molar mass of 118.18 g/mol. It is a colorless liquid with a fruity odor, and it is commonly used as a solvent in various industrial applications, including in the production of lacquers, varnishes, and dyes. 4-ethoxybutan-1-ol is also used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is important to handle this chemical with care, as it can be harmful if ingested, inhaled, or in contact with the skin or eyes, and it should be stored and used in well-ventilated areas and with appropriate protective equipment.

InChI:InChI=1/C6H14O2/c1-2-8-6-4-3-5-7/h7H,2-6H2,1H3

Upstream product

• 33691-62-2 3-bromo-2-ethoxy-tetrahydro-furan 
• 4469-25-4 2-methyl-[1,3]dioxepane 
• 29006-04-0 4-ethoxy-butyric acid methyl ester 
• 64-17-5 ethanol 
• 26448-91-9 4-ethoxy-butyric acid ethyl ester 
• 74-96-4 ethyl bromide 
• 50-00-0 formaldehyd 
• 557-31-3 3-ethoxyprop-1-ene 
• 201230-82-2 carbon monoxide 
• 110-63-4 Butane-1,4-diol 
• 75-03-6 ethyl iodide 
• 109-99-9 tetrahydrofuran 

Downstream Products

• 70160-08-6 6-Ethoxycapronsaeure 
• 60905-39-7 butylene glycol monoethyl ether acetate 
• 90724-84-8 6-Ethoxy-2-methyl-hexanol-(2) 
• 2260-44-8 1-(4-ethoxy-butyl)-4-phenyl-piperidine-4-carboxylic acid ethyl ester 
• 84629-07-2 7-Ethoxy-1-phenyl-1,4-heptandion 
• 29006-04-0 4-ethoxy-butyric acid methyl ester 

Relevant articles and documents

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Synthesis and antiproliferative activity of alkylphosphocholines

Alkylphosphocholines (APC) with one or more methylene groups in the alkyl chain replaced by oxygen atoms or carbonyl groups, or both have been assembled modularly using ω-diols as central building blocks. Out of 25 new compounds of this kind, 11 were evaluated for their antiproliferative activity on four cell lines and compared with miltefosine to evaluate their hemolytic activity (HA) and cytotoxicity on non-tumoral cells (MT2), used as markers of adverse effects. Compound 13 was more active on cancer cell lines than on non-tumoral cells and the data were similar for MTT and thymidine incorporation assays. It had less HA than miltefosine. Compound 13 could therefore be a candidate for the preparation of compounds with higher cytotoxicity on cancer cells and lower general toxicity.

Isomerization and Hydrogenolysis of 1,3-Dioxacycloalkanes on Metal Catalysts

The isomerization of 5-, 6-, and 7-membered 1,3-dioxacycloalkanes to esters on various metal catalysts is reported, the hydrogenolysis pattern for this type of compound is determined, and a new reaction mechanism is proposed to interpret these catalytic processes.