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111035-65-5

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  • 2(5H)-Furanone,5-methyl-3-[(2R,8R,13R)-2,8,13-trihydroxy-13-[(2R,5R)-tetrahydro-5-[(1R)-1-hydroxytridecyl]-2-furanyl]tridecyl]-,(5S)- 111035-65-5

    Cas No: 111035-65-5

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111035-65-5 Usage

Uses

(+/-) Annonacin is used as a modulation of cancer signaling pathway(s) in two -stage mouse skin tumorigenesis by annonacin. Its also used in the evaluation of nutritional characteristics and bioactive compounds of Annona muricata-yogurt and Annona muricata-frozen dessert.

Check Digit Verification of cas no

The CAS Registry Mumber 111035-65-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,1,0,3 and 5 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 111035-65:
(8*1)+(7*1)+(6*1)+(5*0)+(4*3)+(3*5)+(2*6)+(1*5)=65
65 % 10 = 5
So 111035-65-5 is a valid CAS Registry Number.
InChI:InChI=1/C35H64O7/c1-3-4-5-6-7-8-9-10-11-15-21-33(38)34-23-22-32(42-34)27-40-24-17-16-19-30(36)18-13-12-14-20-31(37)26-29-25-28(2)41-35(29)39/h25,28,30-34,36-38H,3-24,26-27H2,1-2H3

111035-65-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-2-methyl-4-[(2R,8R,13R)-2,8,13-trihydroxy-13-[(2R,5R)-5-[(1R)-1-hydroxytridecyl]oxolan-2-yl]tridecyl]-2H-furan-5-one

1.2 Other means of identification

Product number -
Other names Annonacin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:111035-65-5 SDS

111035-65-5Upstream product

111035-65-5Downstream Products

111035-65-5Related news

Data ArticleValidation data for the quantification of the Annonaceous acetogenin annonacin (cas 111035-65-5) in Rat brain by UPLC-MS/MS08/26/2019

Annonaceous acetogenins (AAGs) are environmental neurotoxins from the fruit pulp of several Annonaceae species, whose consumption was linked to the occurrence of sporadic atypical Parkinsonism with dementia. The quantification of the prototypical AAG annonacin in Rat brain homogenates was perfor...detailed

annonacin (cas 111035-65-5) induces cell cycle-dependent growth arrest and apoptosis in estrogen receptor-α-related pathways in MCF-7 cells08/25/2019

Ethnopharmacological relevanceTamoxifen resistance is common in estrogen receptor-α (ERα)-positive breast cancers. Pawpaw and soursop are anticancer annonaceous plants in complementary medicine. Thus, we studied the effects of annonacin, an annonaceous acetogenin, in breast cancer cells.detailed

Method development for quantification of the environmental neurotoxin annonacin (cas 111035-65-5) in Rat plasma by UPLC–MS/MS and application to a pharmacokinetic study08/24/2019

Annonacin is an environmental neurotoxin identified in the pulp of several fruits of the Annonaceae family (for example in Annona muricata, Asimina triloba), whose consumption was linked with the occurrence of sporadic atypical Parkinsonism with dementia. Pharmacokinetic parameters of this molec...detailed

annonacin (cas 111035-65-5) in Asimina triloba fruit: Implication for neurotoxicity08/23/2019

IntroductionThe acetogenin, annonacin, from the tropical annonaceous plant Annona muricata, is a lipophilic, mitochondrial complex I inhibitor reported to be more toxic than rotenone to mesencephalic neurons. The temperate annonaceous plant Asimina triloba (pawpaw) is native to the Eastern Unite...detailed

Short communicationQuantification of the environmental neurotoxin annonacin (cas 111035-65-5) in Rat brain by UPLC-MS/MS08/22/2019

The Annonaceous acetogenin annonacin is an environmental neurotoxin identified in the pulp of several fruits of the Annonaceae family, whose consumption was linked to the occurrence of sporadic atypical Parkinsonism with dementia. A method for its quantification in Rat brain homogenates by UPLC-...detailed

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