111194-08-2

Basic information

• Product Name: (8R,8'R)-4,4'-dibenzyloxy-3,3'-dimethoxylignane-9,9'-diol
• Synonyms: (8R,8'R)-4,4'-dibenzyloxy-3,3'-dimethoxylignane-9,9'-diol
• CAS NO: 111194-08-2
• Molecular Weight: 542.672
• Mol File: 111194-08-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (8R,8'R)-4,4'-dibenzyloxy-3,3'-dimethoxylignane-9,9'-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (8R,8'R)-4,4'-dibenzyloxy-3,3'-dimethoxylignane-9,9'-diol(111194-08-2)
• EPA Substance Registry System: (8R,8'R)-4,4'-dibenzyloxy-3,3'-dimethoxylignane-9,9'-diol(111194-08-2)

Safety Data

• Hazardous Substances Data: 111194-08-2(Hazardous Substances Data)

Upstream product

• 111266-00-3 (R)-4-<(4-hydroxy-3-methoxyphenyl)methyl>dihydro-2(3H)-furanone 
• 100-44-7 benzyl chloride 
• 111266-03-6 (R)-(+)-3-(4-benzyloxy-3-methoxybenzyl)-γ-butyrolactone 
• 72724-00-6 1-(benzyloxy)-4-(bromomethyl)-2-methoxybenzene 
• 111194-07-1 (3R,4R)-3,4-bis(4-benzyloxy-3-methoxybenzyl)dihydrofuran-2(3H)-one 

Downstream Products

• 1612227-16-3 (8R,8'R)-3,3'-dimethoxy-4,4',9-liganetriol 
• 1612227-52-7 C₃₄H₃₆O₅ 
• 1612227-51-6 C₃₄H₃₈O₅ 
• 848844-79-1 (8R,8'R)-4,4'-dihydroxy-3,3'-dimethoxylignane-9,9'-diyl diacetate 
• 1612227-22-1 (8R,8'R)-9-(N,N-dimethylamino)-3,3'-dimethoxylignane-4,4'-diol 
• 1612227-21-0 (8R,8'R)-3,3'-dimethoxy-9a,9b,9b-trihomolignane-4,4'-diol 
• 1612227-20-9 (8R,8'R)-3,3'-dimethoxy-9a,9b,9c,9d-tetrahomolignane-4,4'-diol 
• 1612227-19-6 (8R,8'R)-9-fluoro-3,3'-dimethoxy-4,4'-lignanediol 
• 1612227-18-5 (8R,8′R)-3,3',9,-trimethoxy-4,4'-lignanediol 
• 1612227-17-4 (8R,8'R)-3,3'-dimethoxy-4,4'-dihydroxyligan-9-yl acetate 

Relevant articles and documents

Cytotoxic activity of dietary lignan and its derivatives: Structure-cytotoxic activity relationship of dihydroguaiaretic acid

Cytotoxic activities of synthesized lignan derivatives were estimated by WST-8 reduction assay against HL-60 and HeLa cells to show the structure-activity relationship. The activities of some effective compounds were examined against Colon 26 and Vero cel

THE SYNTHESES OF (R)-(+)-β-VANILLYL-γ-BUTYROLACTONE AND OF CHIRAL LIGNANS THEREFROM

(R)-(+)-β-vanillyl-γ-butyrolactone was obtained in 4 steps including a resolution, from vanillin and dimethyl succinate, and was used for the total syntheses of 5 naturally occurring and optically active lignans such as (+)-isolariciresinol 20.