111269-43-3

Basic information

• Product Name: 1,2-Propanedione, 3,3,3-trifluoro-1-(2-nitrophenyl)-, 1-(dimethylhydrazone)
• CAS NO: 111269-43-3
• Molecular Formula: C11H10F3N3O3
• Molecular Weight: 289.214
• Mol File: 111269-43-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,2-Propanedione, 3,3,3-trifluoro-1-(2-nitrophenyl)-, 1-(dimethylhydrazone)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Propanedione, 3,3,3-trifluoro-1-(2-nitrophenyl)-, 1-(dimethylhydrazone)(111269-43-3)
• EPA Substance Registry System: 1,2-Propanedione, 3,3,3-trifluoro-1-(2-nitrophenyl)-, 1-(dimethylhydrazone)(111269-43-3)

Safety Data

• Hazardous Substances Data: 111269-43-3(Hazardous Substances Data)

Upstream product

• 10424-94-9 2-nitrobenzaldehyde 2,2-dimethylhydrazone 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 118110-46-6 3,3,3-Trifluoro-2-hydroxy-1-(2-nitro-phenyl)-propan-1-one 
• 111269-52-4 3-Methyl-5-(2-nitro-phenyl)-6-trifluoromethyl-3,6-dihydro-2H-[1,3,4]oxadiazine 
• 111269-51-3 1-Methyl-4-(2-nitro-phenyl)-5-trifluoromethyl-1H-imidazole 
• 111269-63-7 3,3,3-Trifluoro-1-(2-nitro-phenyl)-propane-1,2-dione 

Relevant articles and documents

Electrophilic Substitution at Azomethine Carbon Atoms. Reaction of Aromatic Aldehyde Hydrazones with Trifluoroacetic Anhydride

Reaction of dimethylhydrazones of aromatic aldehydes with trifluoroacetic anhydride at room temperature affords high yields of products bearing trifluoroacetyl groups.These electrophilic substitution reactions generally occur on the azomethine carbon, although competitive N-acylation is observed in highly electron-rich systems.Use of diisopropylhydrazones suppressed this N-acylation completely, leading to high yields of C-acylated products.The trifluoroacetyl hydrazones can be cyclized thermally to imidazole and oxadiazine derivatives and can be converted into 1-trifluoromethyl 1,2-diketones by acid hydrolysis.