1114547-55-5

Basic information

• Product Name: 2-chloro-3-fluoro-4-iodo-benzonitrile
• Synonyms: 2-chloro-3-fluoro-4-iodo-benzonitrile
• CAS NO: 1114547-55-5
• Molecular Weight: 281.455
• Mol File: 1114547-55-5.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2-chloro-3-fluoro-4-iodo-benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-3-fluoro-4-iodo-benzonitrile(1114547-55-5)
• EPA Substance Registry System: 2-chloro-3-fluoro-4-iodo-benzonitrile(1114547-55-5)

Safety Data

• Hazardous Substances Data: 1114547-55-5(Hazardous Substances Data)

Upstream product

• 143360-05-8 N-(4-bromo-3-chloro-2-fluorophenyl)acetamide 
• 2106-04-9 3-chloro-2-fluoroaniline 
• 115843-99-7 4-bromo-3-chloro-2-fluoroaniline 
• 757247-99-7 4-amino-2-chloro-3-fluorobenzonitrile 

Relevant articles and documents

CONDENSED BI-HETEROCYCLES AS INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE

Provided are compounds of Formula (I): Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, A1, B1, B2, Q1 and Q2 are as defined herein; and methods for their use and production.

ISOQUINOLINE COMPOUNDS AND USES THEREOF

Isoquinoline compounds of formula (I) variations thereof, and their use as inhibitors of HPK1 (hematopoietic kinase 1) are described. The compounds are useful in treating HPK1-dependent disorders and enhancing an immune response. Also described are methods of inhibiting HPK1, methods of treating HPK1-dependent disorders, methods for enhancing an immune response, and methods for preparing the isoquinoline compounds.

ISOQUINOLINE COMPOUNDS FOR THE TREATMENT OF CANCER

3-Carbonylaminoisoquinoline compounds of formula (I): variations thereof, and their use as inhibitors of HPK1 (hematopoietic kinase 1) are described. The compounds are useful in treating HPK1-dependent disorders and enhancing an immune response. Also described are methods of inhibiting HPK1, methods of treating HPK1-dependent disorders, methods for enhancing an immune response, and methods for preparing the 3-carbonylaminoisoquinoline compounds.