111886-98-7

Basic information

• Product Name: 2-Pyrrolidinone, 5-[(trimethylsilyl)ethynyl]-
• CAS NO: 111886-98-7
• Molecular Formula: C9H15NOSi
• Molecular Weight: 181.31
• Mol File: 111886-98-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Pyrrolidinone, 5-[(trimethylsilyl)ethynyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinone, 5-[(trimethylsilyl)ethynyl]-(111886-98-7)
• EPA Substance Registry System: 2-Pyrrolidinone, 5-[(trimethylsilyl)ethynyl]-(111886-98-7)

Safety Data

• Hazardous Substances Data: 111886-98-7(Hazardous Substances Data)

Upstream product

• 111886-97-6 methyl 4-amino-6-(trimethylsilyl)-5-hexynoate hydrochloride 
• 78389-87-4 ((trimethylsilyl)ethynyl)zinc(II) chloride 
• 84653-52-1 di[1-(3,3-dimethylbut-1-yn)yl]zinc 
• 86976-26-3 5-(phenylthio)pyrrolidin-2-one 

Downstream Products

• 118800-15-0 5-ethynyl-1-methyl-2-pyrrolidone 

Relevant articles and documents

Synthesis of pyrrolizidine alkaloids via rhodium-catalyzed silylformylation and amidocarbonylation

Rhodium-catalyzed silylformylation and amidocarbonylation are applied to the syntheses of pyrrolizidine alkaloids (±)-isoretronecanol and (±)-trachelanthamidine, from 5-ethyl-2-pyrrolidinone.

A NEW AMIDOALKYNYLATION USING ALKYNYLZINC REAGENT

A new amidoalkynylation using alkynylzinc reagent was developed and successfully applied to various α-thio-lactams including 6.