1122-41-4

Basic information

• Product Name: 2,4-DICHLOROTHIOPHENOL
• Synonyms: 2,4-DICHLOROBENZENE-1-THIOL;2,4-DICHLOROBENZENETHIOL;2,4-DICHLOROTHIOPHENOL;2,4-Dichlorothiophenol 98%;2,4-DICHLOROTHIOPHENOL / 2,4-DICHLOROBENZENETHIOL;2,4-Dichlorophenylmercaptan;2,4-Dichlorobenzenethiol,97%;2,4-DICHLOROTHIOPHEN
• CAS NO: 1122-41-4
• Molecular Formula: C₆H₄Cl₂S
• Molecular Weight: 179.07
• EINECS: 214-346-7
• Product Categories: Phenol&Thiophenol&Mercaptan;Phenoles and thiophenoles;Organic Building Blocks;Sulfur Compounds;Thiols/Mercaptans
• Mol File: 1122-41-4.mol
• Article Data: 5

Chemical Properties

• Melting Point: 15°C
• Boiling Point: 60-62 °C1.5 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: clear colorless liquid
• Density: 1.418 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0423mmHg at 25°C
• Refractive Index: n20/D 1.619(lit.)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 5.39±0.48(Predicted)
• Sensitive: Stench
• BRN: 2042868
• CAS DataBase Reference: 2,4-DICHLOROTHIOPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-DICHLOROTHIOPHENOL(1122-41-4)
• EPA Substance Registry System: 2,4-DICHLOROTHIOPHENOL(1122-41-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/38
• Safety Statements: 26-36
• RIDADR: 2810
• WGK Germany: 3
• HazardClass: IRRITANT, STENCH
• PackingGroup: III
• Hazardous Substances Data: 1122-41-4(Hazardous Substances Data)

Usage

Description

2,4-Dichlorothiophenol is a halogenated aromatic thiol, which is a clear colorless liquid. It is a chemical compound with the molecular formula C6H4Cl2S, where two chlorine atoms are attached to the 2nd and 4th carbon atoms of a thiophene ring.

Uses

Used in Polymer Industry:
2,4-Dichlorothiophenol is used as a monomer for the preparation of hyperbranched poly(phenylene sulfide) (HPPS). This polymer is known for its excellent thermal stability, mechanical properties, and chemical resistance, making it suitable for various applications in the polymer industry.
Used in Electronics Industry:
In the electronics industry, 2,4-dichlorothiophenol is utilized for the functionalization of printed gold nanoparticle films. This functionalization enhances the properties of the films, allowing for improved performance in electronic devices and components.
Used in Chemical Synthesis:
2,4-Dichlorothiophenol is used as a key intermediate in the synthesis of N,N-dialkyl(aminopropyl)amino diaryl sulphide. 2,4-DICHLOROTHIOPHENOL has potential applications in various chemical processes and products, such as pharmaceuticals and agrochemicals, due to its unique chemical properties.

InChI:InChI=1/C6H4Cl2S/c7-4-1-2-6(9)5(8)3-4/h1-3,9H/p-1

Upstream product

• 16271-33-3 2,4-Dichlorobenzenesulfonyl chloride 
• 140-89-6 potassium ethyl xanthogenate 
• 554-00-7 2,4-Dichloroaniline 
• 120-82-1 1,2,4-Trichlorobenzene 

Downstream Products

• 42583-60-8 2,4-dichlorophenyl 4′-nitrophenyl sulfide 
• 78483-29-1 chloromethyl-(2,4-dichloro-phenyl)-sulfide 
• 15433-50-8 1,2-bis(2,4-dichlorophenyl)disulfane 
• 7720-41-4 2-(2,4-dichlorophenylsulfanyl)acetic acid 
• 876493-12-8 (2-chloro-ethyl)-(2,4-dichloro-phenyl)-sulfide 
• 21106-10-5 2,4-Dichlor-phenyl-sulfinylmethylthiocyanat 
• 22218-74-2 2,4-Dichlor-phenyl-sulfonylmethyl-thiocyanat 
• 17119-40-3 5-(2,4-dichloro-phenylsulfanyl)-4-methyl-thiazol-2-ylamine 
• 86026-57-5 1-{2-[2-(2,4-Dichloro-phenylsulfanyl)-ethyl]-pyrrolidin-1-yl}-ethanone 
• 62858-46-2 2,2',4,4'-Tetrachlordibenzolsulfenamid 
• 180622-74-6 1-(5-Bromo-pentylsulfanyl)-2,4-dichloro-benzene 
• 311808-47-6 3-[(2,4-dichlorophenyl)thio]benzoic acid 
• 53316-76-0 2-(2,4-dichloro-benzenesulfonyl)-5-nitro-thiazole 
• 124474-24-4 2-[[(2,4-dichlorophenyl)dithio]methyl]-4-methoxy-3-methyl-1-(1,5,6,7-tetrahydro-5,5,7,7-tetramethyl-6-oxoindeno[5,6-d]imidazol-2-yl)pyridinium chloride 

Relevant articles and documents

S-aryl(tetramethyl)isothiouronium salts as possible antimicrobial agents - III

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Quantitative Structure-Activity Analysis in Dihydropteroate Synthase Inhibition by Sulfones. Comparison with Sulfanilamides

A set of 25 4'-, eight 2',4'-, and five 2',4',6'-substituted 4-aminodiphenyl sulfones were tested for their inhibitory activity on dihydropteroate synthase of Escherichia coli.Linear regression analysis shows that enzymic inhibition indices correlate well with both quantum chemical and spectroscopic descriptors of the electronic structure of the common moiety 4-NH2-C6H4-SO2 of the sulfones (the above descriptors being expressed in relation to the electronic structure of the enzyme substrate, p-aminobenzoate).Therefore, the biological activity of the sulfones can be related to the electronic structural resemblance between these inhibitors and the substrate of the target enzyme.Since a similar result was previously obtained for a wide series of sulfanilamides in their different (amidic, imidic, and anionic) forms, it appears possible to consider the antibacterial sulfones and sulfanilamides as a congeneric chemical series.On the basis of the present results, the classical theory of antimetabolites would appear to take on a quantitative and sound rationale.

Antidiabetic pyrrolecarboxylic acids

Certain pyrrolecarboxylic and pyrroleacetic acid derivatives substituted on the pyrrole ring with thioether groups, acyl groups, phenyl, substituted phenyl, phenoxy, substituted phenoxy, benzyl or halo and optionally substituted on the pyrrole nitrogen with alkyl, and the pharmaceutically acceptable salts thereof, are useful in lowering the blood glucose levels of hyperglycemic animals.