112251-18-0

Basic information

• Product Name: 17β-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy>-5α-androstan-3-one
• Synonyms: 17β-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy>-5α-androstan-3-one
• CAS NO: 112251-18-0
• Molecular Weight: 506.504
• Mol File: 112251-18-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 17β-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy>-5α-androstan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 17β-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy>-5α-androstan-3-one(112251-18-0)
• EPA Substance Registry System: 17β-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy>-5α-androstan-3-one(112251-18-0)

Safety Data

• Hazardous Substances Data: 112251-18-0(Hazardous Substances Data)

Upstream product

• 521-18-6 Stanolone 
• 434-64-0 perfluorotoluene 
• 112251-17-9 3,17β-bis-<2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenoxy>-5α-androst-2-ene 

Relevant articles and documents

The Selective Protection of the 3-Ketone Functions of Steroids as Heptafluoro-p-tolyl Enol Ethers

Conjugated and unconjugated 3-ketone functions in steroids react with octafluorotoluene at above 100 deg C in the presence of caesium fluoride to give heptafluoro-p-tolyl enol ethers.The related but unusually reactive Wieland-Miescher ketone (11) reacted at room temperature in the presence of tetra-n-butylammonium fluoride.Enones were regenerated from their derivatives by acidic hydrolysis.Hydrolysis of the derivative (10) of 4,5α-dihydroxytestosterone was slu but sodium methoxide regenerated the parent steroid.The methods have been applied in a synthesis of deuterium-labelled testosterone.