112318-61-3

Basic information

• Product Name: (+)-2β,3β,5β-trihydroxycyclopentyl-1β-acetic acid γ-lactone
• Synonyms: (+)-2β,3β,5β-trihydroxycyclopentyl-1β-acetic acid γ-lactone
• CAS NO: 112318-61-3
• Molecular Weight: 158.154
• Mol File: 112318-61-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+)-2β,3β,5β-trihydroxycyclopentyl-1β-acetic acid γ-lactone(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-2β,3β,5β-trihydroxycyclopentyl-1β-acetic acid γ-lactone(112318-61-3)
• EPA Substance Registry System: (+)-2β,3β,5β-trihydroxycyclopentyl-1β-acetic acid γ-lactone(112318-61-3)

Safety Data

• Hazardous Substances Data: 112318-61-3(Hazardous Substances Data)

Upstream product

• 34638-25-0 (1R,5S)-2-oxabicyclo[3.3.0]oct-6-en-3-one 

Downstream Products

• 112168-53-3 (+)-1β-methoxycarbonylmethyl-2β,3β-(p-nitrobenzylidene)-dioxycyclopentan-5-one 
• 112168-52-2 (+)-5β-hydroxy-1β-methoxycarbonylmethyl-2β,3β-(p-nitrobenzylidene)-dioxycyclopentane 
• 112168-48-6 (+)-1β-carboxymethyl-5β-hydroxy-2β,3β-(p-nitrobenzylidene) dioxycyclopentane 
• 112168-46-4 (+)-5β-hydroxy-2β,3β-(p-nitrobenzylidene)-dioxycyclopentyl-1β-acetic acid γ-lactone 

Relevant articles and documents

Intermediates of Prostanoid Synthesis, Stereospecific Conversion of (+)-5β-Hydroxycyclopenten-2-yl-1β-acetic Acid γ-lactone into (+)-1β-Methoxycarbonylmethyl-2β,3β-(p-nitrobenzylidene)-dioxycyclopentan-5-one

Starting from (+)-5β-hydroxycyclopenten-2-yl-1β-acetic acid γ-lactone (1), (+)-1β-methoxycarbonylmethyl-2β,3β-(p-nitrobenzylidene)-dioxycyclopentan-5-one (7) was prepared within 4 steps.Subsequent cleavage of the latter gives (-)-3β-hydroxy-1-methoxy-carbonylmethylcyclopent-1-en-5-one (8a).Hydroxylation of the lactone (1) was found to give (+)-2β,3β,5β-trihydroxycyclopentyl-1β-acetic acid γ-lactone (2a) with cis-oriented hydroxy groups in respect to the lactone ring.No formation of the trans-isomer, as has been reported earlier, was observed.