112370-46-4

Basic information

• Product Name: (2R,3S)-2-(4-Chloro-benzenesulfonyl)-dodecane-1,3-diol
• Synonyms: (2R,3S)-2-(4-Chloro-benzenesulfonyl)-dodecane-1,3-diol
• CAS NO: 112370-46-4
• Molecular Weight: 376.945
• Mol File: 112370-46-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3S)-2-(4-Chloro-benzenesulfonyl)-dodecane-1,3-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3S)-2-(4-Chloro-benzenesulfonyl)-dodecane-1,3-diol(112370-46-4)
• EPA Substance Registry System: (2R,3S)-2-(4-Chloro-benzenesulfonyl)-dodecane-1,3-diol(112370-46-4)

Safety Data

• Hazardous Substances Data: 112370-46-4(Hazardous Substances Data)

Upstream product

• 112388-99-5 (R)-1-Chloro-3-(4-chloro-benzenesulfonyl)-propan-2-ol 
• 74603-09-1 (S)-2-(4-Chloro-benzenesulfonylmethyl)-oxirane 
• 84445-74-9 1-(p-chlorophenylsulfonyl)-3-chloro-2-propanone 
• 17049-49-9 octylmagnesium bromide 
• 50-00-0 formaldehyd 
• 112388-98-4 (S)-1-(4-Chloro-benzenesulfonyl)-undecan-2-ol 

Downstream Products

• 4048-42-4 1-dodecen-3-ol 
• 112370-41-9 Toluene-4-sulfonic acid (2R,3S)-2-(4-chloro-benzenesulfonyl)-3-hydroxy-dodecyl ester 

Relevant articles and documents

Reactions of (2S)-1-Arenesulfonyl-2-alkanol Dianions with Aldehydes. Application to the Synthesis of Enantiomerically Pure (3S)-1-Alken-3-ols and (2E,4S)-4-hydroxy-2-alkenenitriles

Enantiomerically pure (2S)-1-arenesulfonyl-2-alkanols (1) were prepared by yeast reduction of 1-arenesulfonyl-3-chloro-2-propanones, followed by epoxydation and alkylation.Reaction of dianions of 1 with aldehydes occurred at the pro(R) position of C(1) to give 1,3-diols, which were converted to (3S)-1-alken-3-ols or (2E,4S)-4-hydroxy-2-alkenenitriles in 100percent e.e.