112598-77-3

Basic information

• Product Name: 3-(2-FURYL)BENZONITRILE
• Synonyms: 3-(2-FURYL)BENZONITRILE;AKOS BAR-0089;3-FURAN-2-YL-BENZONITRILE;2-(3-Cyanophenyl)furan;3-(Fur-2-yl)benzonitrile
• CAS NO: 112598-77-3
• Molecular Formula: C₁₁H₇NO
• Molecular Weight: 169.18
• Mol File: 112598-77-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 295.2 °C at 760 mmHg
• Flash Point: 132.3 °C
• Appearance: /
• Density: 1.18 g/cm³
• Vapor Pressure: 0.00155mmHg at 25°C
• Refractive Index: 1.596
• CAS DataBase Reference: 3-(2-FURYL)BENZONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-FURYL)BENZONITRILE(112598-77-3)
• EPA Substance Registry System: 3-(2-FURYL)BENZONITRILE(112598-77-3)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 112598-77-3(Hazardous Substances Data)

Usage

General Description

3-(2-furyl)benzonitrile is a chemical compound with the molecular formula C12H7NO. It is a yellowish liquid that is used in the production of pharmaceuticals and organic synthesis. This chemical is commonly referred to as 2-furanbenzonitrile or 2-furyl benzonitrile and is known for its strong odor. 3-(2-furyl)benzonitrile is also used as a building block in the synthesis of various organic compounds and is considered to be a potentially hazardous substance. It is important to handle this chemical with care and take proper safety precautions when working with it.

InChI:InChI=1/C11H7NO/c12-8-9-3-1-4-10(7-9)11-5-2-6-13-11/h1-7H

Upstream product

• 110-00-9 furan 
• 2237-30-1 m-cyanoaniline 
• 69113-59-3 3-iodobenzonitrile 
• 118486-94-5 2-(tributylstannyl)furan 

Downstream Products

• 453568-72-4 3-(5-bromofuran-2-yl)-5-fluoro-benzonitrile 
• 112598-80-8 3-(5-Dimethylaminomethyl-furan-2-yl)-benzylamine 
• 112598-79-5 3-(5-Dimethylaminomethyl-furan-2-yl)-benzonitrile 

Relevant articles and documents

UiO-66 microcrystals catalyzed direct arylation of enol acetates and heteroarenes with aryl diazonium salts in water

UiO-66 is a classic Metal–organic framework (MOF) that constructed by zirconium cations and terephthalate with high chemical and thermal stability. Using pristine UiO-66 nanocrystals as the catalysts, the carbon–carbon bond formation based on denitrogenat

Molecular Design of Donor-Acceptor-Type Organic Photocatalysts for Metal-free Aromatic C?C Bond Formations under Visible Light

Metal-free and photocatalytic radical-mediated aromatic C?C bond formations offer a promising alternative pathway to the conventional transition metal-catalyzed cross-coupling reactions. However, the formation of aryl radicals from common precursors such as aryl halides is highly challenging due to their extremely high reductive potential. Here, we report a structural design strategy of donor-acceptor-type organic photocatalysts for visible light-driven C?C bond formations through the reductive dehalogenation of aryl halides. The reduction potential of the photocatalysts could be systematically aligned to be ?2.04 V vs. SCE via a simple heteroatom engineering of the donor-acceptor moieties. The high reductive potential of the molecular photocatalyst could reduce various aryl halides into aryl radicals to form the C?C bond with heteroarenes. The designability of the molecular photocatalyst further allowed the synthesis of a high LUMO (lowest unoccupied molecular orbital) polymer photocatalyst by a self-initiated free radical polymerization without compromising its LUMO level. (Figure presented.).

Palladium on charcoal-catalyzed ligand-free Stille coupling

An efficient ligand-free Stille coupling reaction catalyzed by palladium on charcoal was developed. Tetraphenyltin was reacted with a variety of aryl halides including aryl chlorides using LiCl as an additive. The reactions of tributyl organotin compounds with aryl iodides were effectively expedited by the addition of LiF. These reactions efficiently proceeded without a phosphine or arsenic ligand and no leached palladium was detected in the reaction mixture.