112953-45-4

Basic information

• Product Name: Acetic acid, [(5-methyl-4-oxo-3-phenyl-4H-1-benzopyran-7-yl)oxy]-
• CAS NO: 112953-45-4
• Molecular Formula: C18H14O5
• Molecular Weight: 310.306
• Mol File: 112953-45-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Acetic acid, [(5-methyl-4-oxo-3-phenyl-4H-1-benzopyran-7-yl)oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, [(5-methyl-4-oxo-3-phenyl-4H-1-benzopyran-7-yl)oxy]-(112953-45-4)
• EPA Substance Registry System: Acetic acid, [(5-methyl-4-oxo-3-phenyl-4H-1-benzopyran-7-yl)oxy]-(112953-45-4)

Safety Data

• Hazardous Substances Data: 112953-45-4(Hazardous Substances Data)

Upstream product

• 112953-75-0 (5-Methyl-4-oxo-3-phenyl-4H-chromen-7-yloxy)-acetic acid ethyl ester 
• 55338-30-2 7-hydroxy-5-methyl-3-phenyl-chromen-4-one 
• 4179-19-5 1,3-dimethoxy-5-methylbenzene 
• 860579-89-1 1-(2-hydroxy-4-methoxy-6-methylphenyl)-2-phenylethan-1-one 
• 82517-12-2 5-methyl-7-methoxyisoflavone 
• 103-80-0 phenylacetyl chloride 

Relevant articles and documents

Aryloxyacetic acid diuretics with uricosuric activity. II. Substituted [(4-oxo-4H-1-benzopyran-7-yl)oxy]acetic acids and the related compounds

Di- and tri-substituted [(4-oxo-4H-1-benzopyran-7-yl)oxy]acetic acids, and 4-oxo-3-phenyl-4H-furo[2,3-h][1]benzopyran-8-carboxylic acid were synthesized and tested for natriuretic and uricosuric activities. Among the compounds tested, 3,5-disubstituted [(4-oxo-4H-1-benzopyran-7-yl)oxy]acetic acids (6c-f, h, n and x) showed potent natriuretic and uricosuric activities, whereas 4-oxo-3-phenyl-4H-furo[2,3-h][1]benzopyran-8-carboxylic acid (6dd) possessed only potent natriuretic activity. The structure-activity relationships are also discussed.