1132-66-7

Basic information

• Product Name: hexyl phenyl ether
• Synonyms: hexyl phenyl ether;hexyloxybenzene;Phenylhexyl ether
• CAS NO: 1132-66-7
• Molecular Formula: C₁₂H₁₈O
• Molecular Weight: 178.27
• Mol File: 1132-66-7.mol
• Article Data: 32

Chemical Properties

• Melting Point: -19°C
• Boiling Point: 240°C (estimate)
• Flash Point: 92.4°C
• Appearance: /
• Density: 0.9174
• Vapor Pressure: 0.0602mmHg at 25°C
• Refractive Index: 1.4921 (estimate)
• CAS DataBase Reference: hexyl phenyl ether(CAS DataBase Reference)
• NIST Chemistry Reference: hexyl phenyl ether(1132-66-7)
• EPA Substance Registry System: hexyl phenyl ether(1132-66-7)

Safety Data

• Hazardous Substances Data: 1132-66-7(Hazardous Substances Data)

Usage

General Description

Hexyl phenyl ether, also known as n-hexyl phenyl ether, is an organic compound consisting of a phenyl group attached to a hexyl chain. It is a colorless liquid with a faint floral odor, and is insoluble in water but soluble in most organic solvents. Hexyl phenyl ether is commonly used as a solvent in various industrial applications, such as in the formulation of coatings, adhesives, and inks. It also finds use as a fragrance ingredient in perfumes and cosmetics. In addition, it has been studied for its potential use as a heat transfer fluid due to its high thermal stability and low viscosity. Hexyl phenyl ether is considered to have low toxicity, but should still be handled with care and in accordance with proper safety guidelines.

InChI:InChI=1/C12H18O/c1-2-3-4-8-11-13-12-9-6-5-7-10-12/h5-7,9-10H,2-4,8,11H2,1H3

Upstream product

• 544-10-5 1-Chlorohexane 
• 139-02-6 sodium phenoxide 
• 111-25-1 1-bromo-hexane 
• 51795-97-2 6-bromohexyloxybenzene 
• 122-79-2 Phenyl acetate 
• 3839-35-8 4-methylbenzenesulfonic acid n-hexylester 
• 60-29-7 diethyl ether 
• 920-39-8 isopropylmagnesium bromide 
• 861571-88-2 (5-iodo-hexyl)-phenyl ether 
• 346621-45-2 ((6-iodohexyl)oxy)benzene 
• 4279-76-9 phenoxyacetylene 
• 584-08-7 potassium carbonate 
• 638-45-9 1-Iodohexane 
• 108-95-2 phenol 

Downstream Products

• 41297-22-7 4-oxo-4-(4-hexyloxy-phenyl)-trans-crotonic acid 
• 64779-14-2 4-(4-hexyloxy-phenyl)-4-oxo-butyric acid 
• 5736-95-8 4-hexyloxyacetophenone 
• 104192-32-7 1,6-Bis-(4-hexyloxy-phenyl)-hexane-1,6-dione 
• 5736-96-9 1-(4-(hexyloxy)phenyl)propan-1-one 
• 67962-85-0 p-n-hexyloxyphenyl n-propyl ketone 
• 15560-78-8 ethyl 2-(4-(n-hexyloxy)phenyl)acetate 
• 6345-84-2 1-chloro-4-(hexyloxy)benzene 
• 638-45-9 1-Iodohexane 
• 108-95-2 phenol 
• 39496-57-6 6-(4-hexyloxy-phenyl)-4,5-dihydro-2H-pyridazin-3-one 
• 1240-61-5 2-<4-Hexyloxy-phenylmercaptomethyl>-benzoesaeure 
• 64328-71-8 2-bromo-1-(4-hexyloxy-phenyl)-ethanone 
• 1038526-42-9 4,4′-dihexyloxybenzil 

Relevant articles and documents

Reduced Phenalenyl in Catalytic Dehalogenative Deuteration and Hydrodehalogenation of Aryl Halides

Dehalogenative deuteration reactions are generally performed through metal-mediated processes. This report demonstrates a mild protocol for hydrodehalogenation and dehalogenative deuteration of aryl/heteroaryl halides (39 examples) using a reduced odd alternant hydrocarbon phenalenyl under transition metal-free conditions and has been employed successfully for the incorporation of deuterium in various biologically active compounds. The combined approach of experimental and theoretical studies revealed a single electron transfer-based mechanism.

Silylarene Hydrogenation: A Strategic Approach that Enables Direct Access to Versatile Silylated Saturated Carbo- and Heterocycles

We report a method to convert readily available silylated arenes into silylated saturated carbo- and heterocycles by arene hydrogenation. The scope includes alkoxy- and halosilyl substituents. Silyl groups can be derivatized into a plethora of functionalities and find application in organic synthesis, materials science, and pharmaceutical, agrochemical, and fragrance research. However, silylated saturated (hetero-) cycles are difficult to access with current technologies. The yield of the hydrogenation depends on the amount of the silica gel additive. This silica effect also enables a significant improvement of a previously disclosed method for the hydrogenation of highly fluorinated arenes (e.g., to all-cis-C6H6F6).

Conversion of Cyclohexanones to Alkyl Aryl Ethers by Using a Pd/C–Ethylene System

The conversion of cyclohexanone and substituted cyclohexanones into alkyl aryl ethers by using a Pd/C–ethylene system is discussed, with ethylene functioning as a hydrogen acceptor. The ether products are easily transformed into the corresponding phenols by treatment with BBr3. The direct conversion of cyclohexenone into phenol in the presence of a catalytic amount of Pd/C under an ethylene atmosphere is also described.