113277-24-0

Basic information

• Product Name: 2-Propenoic acid, 3-(4-hydroxyphenyl)-2-methyl-, (2E)-
• CAS NO: 113277-24-0
• Molecular Formula: C10H10O3
• Molecular Weight: 178.188
• Mol File: 113277-24-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 3-(4-hydroxyphenyl)-2-methyl-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 3-(4-hydroxyphenyl)-2-methyl-, (2E)-(113277-24-0)
• EPA Substance Registry System: 2-Propenoic acid, 3-(4-hydroxyphenyl)-2-methyl-, (2E)-(113277-24-0)

Safety Data

• Hazardous Substances Data: 113277-24-0(Hazardous Substances Data)

Upstream product

• 516-05-2 methyl-propanedioic acid 
• 123-08-0 4-hydroxy-benzaldehyde 
• 123-62-6 propionic acid anhydride 
• 327-62-8 potassium propionate 

Downstream Products

• 1579197-44-6 C₄₂H₇₄O₁₀Si₃ 
• 1579198-21-2 C₄₂H₆₄N₆O₁₁Si₂ 
• 1579197-48-0 C₄₀H₇₂O₉Si₃ 
• 1579197-51-5 C₃₆H₆₂O₉Si₂ 
• 1579197-53-7 C₄₀H₇₀O₉Si₃ 
• 1579197-55-9 C₄₁H₇₂O₉Si₃ 
• 1579197-57-1 C₄₁H₇₂O₉Si₃ 
• 1579197-59-3 C₁₈H₂₀O₉ 
• 1579198-19-8 C₅₄H₉₂N₆O₁₁Si₄ 
• 1579198-23-4 C₅₃H₉₂N₆O₁₀Si₄ 
• 1579198-25-6 C₆₈H₁₁₀N₆O₁₅Si₄ 
• 37305-78-5 A₂₀₁A 
• 1579198-28-9 C₁₈H₂₀O₉ 
• 1579198-30-3 C₃₀H₃₆N₆O₁₁ 

Relevant articles and documents

Synthesis of Albicidin Derivatives: Assessing the Role of N-terminal Acylation on the Antibacterial Activity

The peptide antibiotic albicidin, which is synthesized by the plant pathogenic bacterium, Xanthomonas albilineans, represents the most prominent member of a new class of antibacterial gyrase inhibitors. It shows remarkable antibacterial activities against Gram-positive and Gram-negative microorganisms. Its unique structure potentially represents a new lead structure for the development of an antibacterial drug. Here we report the synthesis of 14 albicidin derivatives with structural variations at the N-terminus, primarily investigating the effects of variation of cinnamoyl, phenylpropanoyl, and benzoyl residues. Gyrase inhibition in vitro and determination of minimal inhibitory concentrations were assessed in parallel. Activities in a nanomolar range and the importance of N-acylation were demonstrated.

Synthetic modification of the 2-oxypropionic acid moiety in 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid (XK469), and consequent antitumor effects. Part 4

The criteria for the activity of 2-{4-[(7-chloro-2-quinoxalinyl)oxy] phenoxy}propionic acid (XK469) and 2-{4-[(7-bromo-2-quinolinyl)oxy]phenoxy} propionic acid (SH80) against transplanted tumors in mice established in previous studies, require a (7-halo-2

Phenylcarboxylic acid derivatives

Phenylcarboxylic acid derivatives having the formula: STR1 wherein R1 and R2 are each H, halogen, alkyl, haloalkyl, alkanoyl, cycloalkyl, nitro, amino, --O--D--R5 (D is alkylene, R5 is H, amino, morpholino, carboxyl, phthalimido, phenyl, epoxy), substituted or unsubstituted phenoxy, substituted or unsubstituted phenylalkylamino, carboxylalkenyl, or both form alkylenedioxy; R3 is H, --E--R6 (E is alkylene, R6 is H, carboxyl, cyano, OH, phenylalkoxy, or halogen-substituted phenyl, or phenylcarbamoyl), --CO--G--R7 (G is alkylene, R7 is H, substituted or unsubstituted phenylcarbamoyl), substituted or unsubstituted benzoyl, alkenyl, carbamoyl, phenyl, or halophenyl; R4 is H or alkyl; A is alkylene, alkylene condensed with cycloalkyl ring, or alkenylene; B is alkylene or alkenylene; l is 0 or 1. Said compounds have fatty acid synthesis-inhibitory activity, cholesterol synthesis-inhibitory activity and are useful as antilipidemic agent, prophylactic and treating agent of artherosclerosis, prophylactic and treating agent of obesity, antidiabetics.