1134195-54-2

Basic information

• Product Name: C₆₁H₇₇N₆O₁₆PSi₂
• Synonyms: C₆₁H₇₇N₆O₁₆PSi₂
• CAS NO: 1134195-54-2
• Molecular Weight: 1237.46
• Mol File: 1134195-54-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₆₁H₇₇N₆O₁₆PSi₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₆₁H₇₇N₆O₁₆PSi₂(1134195-54-2)
• EPA Substance Registry System: C₆₁H₇₇N₆O₁₆PSi₂(1134195-54-2)

Safety Data

• Hazardous Substances Data: 1134195-54-2(Hazardous Substances Data)

Upstream product

• 118380-84-0 N⁴-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)cytidine 3'-O-(2-cyanoethyl N,N-diisopropylphosphoramidite) 
• 54925-71-2 2'-O-(tert-butyldimethylsilyl)uridine 

Downstream Products

• 1134195-58-6 C₇₀H₉₄N₈O₁₇P₂Si₂ 

Relevant articles and documents

Preparation of Nucleotide Oligomer

The present invention provides a method for preparing nucleotide oligomers, including (a) coupling a nucleotide dimer or nucleotide trimer to a nucleoside attached to solid supports or to universal solid supports as a starting material; (b) sequentially coupling nucleotide monomers to the resulting structures of Step (a) to prepare a nucleotide oligomer; and (c) removing the nucleotide oligomers from the solid supports. The method of the present invention provides nucleotide oligomers having 15-20% higher purity than the conventional art. The present invention enables the efficient and inexpensive synthesis of nucleotide oligomers with high purity within a shorter period of time.