1134849-36-7

Basic information

• Product Name: Z-Asp(OBzl)-Lys(Boc)-OH
• CAS NO: 1134849-36-7
• Molecular Weight: 585.654
• Mol File: 1134849-36-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Z-Asp(OBzl)-Lys(Boc)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Z-Asp(OBzl)-Lys(Boc)-OH(1134849-36-7)
• EPA Substance Registry System: Z-Asp(OBzl)-Lys(Boc)-OH(1134849-36-7)

Safety Data

• Hazardous Substances Data: 1134849-36-7(Hazardous Substances Data)

Upstream product

• 17543-13-4 pentafluorophenyl ester of benzyloxycarbonyl-β-benzylaspartic acid 
• 2418-95-3 (S)-2-amino-6-(tert-butoxycarbonylamino)hexanoic acid 

Relevant articles and documents

Myelopeptide MP-5 and fluorescent derivatives: Synthesis and biological activity

The Val-Val-Tyr-Pro-Asp bone marrow peptide (MP-5) and its analogue (MP-5-Lys) were synthesized. Fluorescent derivatives, Ftc-MP-5 and MP-5-Lys(Ftc), were prepared. The iological activity of MP-5 and MP-5-Lys was studied in vitro and in vivo. The MP-5 peptide caused 60-84% inhibition of growth of the following mouse cancers: lymphatic leukemia P388, melanoma B-16, and cervical carcinoma CUC-5. These peptides also restored functional activity of T-lymphocytes that was inhibited by metabolic products of the HL-60 leukemic cell line. MP-5-Lys(Ftc) was shown to preserve the functional properties of MP-5 towards T-lymphocytes, but Ftc-MP-5 was practically inactive.