113494-44-3

Basic information

• Product Name: 2,4-diamino-5-(3-azido-4-dimethylaminophenyl)-6-ethylpyrimidine
• Synonyms: 2,4-diamino-5-(3-azido-4-dimethylaminophenyl)-6-ethylpyrimidine
• CAS NO: 113494-44-3
• Molecular Weight: 298.351
• Mol File: 113494-44-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,4-diamino-5-(3-azido-4-dimethylaminophenyl)-6-ethylpyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-diamino-5-(3-azido-4-dimethylaminophenyl)-6-ethylpyrimidine(113494-44-3)
• EPA Substance Registry System: 2,4-diamino-5-(3-azido-4-dimethylaminophenyl)-6-ethylpyrimidine(113494-44-3)

Safety Data

• Hazardous Substances Data: 113494-44-3(Hazardous Substances Data)

Upstream product

• 58-14-0 2,4-diamino-5-(4-chlorophenyl)-6-ethylpyrimidine 
• 21813-35-4 2,4-diamino-5-(4-chloro-3-nitrophenyl)-6-ethylpyrimidine 
• 113494-40-9 2,4-diamino-5-<4-(dimethylamino)-3-nitrophenyl>-6-ethylpyrimidine 
• 113494-42-1 2,4-diamino-5-(3-amino-4-dimethylaminophenyl)-6-ethylpyrimidine 

Downstream Products

• 113494-51-2 2,4-diamino-5-(4-dimethylaminophenyl)-6-ethylpyrimidine 

Relevant articles and documents

Structural Studies on Bioactive Compounds. 8. Synthesis, Crystal Structure, and Biological Properties of a New Series of 2,4-Diamino-5-aryl-6-ethylpyrimidine Dihydrofolate Reductase Inhibitors with in Vivo Activity against a Methotrexate-Resistant Tumor C

A series of 2,4-diamino-5-aryl-6-ethylpyrimidines embracing basic substituents in the 5-aryl ring was synthesized and evaluated for inhibitory activity against rat liver dihydrofolate reductase (DHFR).Maximal enzyme inhibition was observed for compounds b