1135339-49-9 Usage
Description
Δ(2,3)-(4S)-ivermectin, also known as Ivermectin Impurity I, is a derivative of Ivermectin (I940800), an antiparasitic drug. It is characterized by its Δ(2,3) double bond and (4S) stereochemistry. Δ(2,3)-(4S)-ivermectin exhibits potent activity against a broad spectrum of nematode and arthropod parasites, making it a valuable pharmaceutical candidate for various applications.
Uses
Used in Pharmaceutical Industry:
Δ(2,3)-(4S)-ivermectin is used as an antiparasitic agent for the treatment of scabies and lice in humans. It is effective against a wide variety of nematode and arthropod parasites, providing relief from these parasitic infections.
Used in Antiviral Applications:
Δ(2,3)-(4S)-ivermectin is used as an in vitro inhibitor of SARS-CoV-2/Covid-19. It has shown potential in inhibiting the replication of the virus, offering a possible therapeutic approach to combat the Covid-19 pandemic.
Check Digit Verification of cas no
The CAS Registry Mumber 1135339-49-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,5,3,3 and 9 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1135339-49:
(9*1)+(8*1)+(7*3)+(6*5)+(5*3)+(4*3)+(3*9)+(2*4)+(1*9)=139
139 % 10 = 9
So 1135339-49-9 is a valid CAS Registry Number.
1135339-49-9Relevant articles and documents
Ivermectin-derived leishmanicidal compounds
Santos, Anderson Rouge dos,Falcao, Camila Alves Bandeira,Muzitano, Michelle Frazao,Kaiser, Carlos Roland,Rossi-Bergmann, Bartira,Ferezou, Jean-Pierre
, p. 496 - 502 (2009)
In the present study a family of macrocyclic and acyclic analogues as well as seco-analogues of avermectins were prepared from commercial Ivermectin (IVM) and their antileishmanial activity assayed against axenic promastigote and intracellular amastigote
