1135389-59-1

Basic information

• Product Name: (1,3-DIOXOLAN-2-YLMETHYL)ZINC BROMIDE
• Synonyms: (1,3-DIOXOLAN-2-YLMETHYL)ZINC BROMIDE;(1,3-Dioxolan-2-ylmethyl)zinc bromide, 0.50 M in THF;(1,3-Dioxolan-2-ylmethyl)zinc bromide, Packaged under Argon in resealable ChemSeal? bottles
• CAS NO: 1135389-59-1
• Molecular Formula: C4H7BrO2Zn
• Molecular Weight: 232.39118
• Mol File: 1135389-59-1.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 0.992 g/mL at 25 °C
• Storage Temp.: 2-8°C
• Water Solubility: Reacts with water.
• CAS DataBase Reference: (1,3-DIOXOLAN-2-YLMETHYL)ZINC BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (1,3-DIOXOLAN-2-YLMETHYL)ZINC BROMIDE(1135389-59-1)
• EPA Substance Registry System: (1,3-DIOXOLAN-2-YLMETHYL)ZINC BROMIDE(1135389-59-1)

Safety Data

• Hazard Codes: F,Xn
• Statements: 11-19-36/37-40
• Safety Statements: 16-26-36/37
• Hazardous Substances Data: 1135389-59-1(Hazardous Substances Data)

Usage

Description

(1,3-Dioxolan-2-ylmethyl)zinc bromide is an organozinc compound characterized by its unique structure that features a 1,3-dioxolan-2-ylmethyl group attached to a zinc atom. (1,3-Dioxolan-2-ylmethyl)zinc bromide is known for its reactivity and utility in various chemical reactions, particularly in the field of organic synthesis.

Uses

Used in Organic Synthesis:
(1,3-Dioxolan-2-ylmethyl)zinc bromide is used as a reagent in Negishi cross-coupling reactions for the formation of aryl or heteroaryl scaffolds via C-C bond formation. This application is significant in the synthesis of complex organic molecules, which are essential in the development of pharmaceuticals, agrochemicals, and advanced materials.
Used in Allylic Alkylation Reactions:
In the presence of an iridium catalyst, (1,3-dioxolan-2-ylmethyl)zinc bromide can be employed as a reagent in allylic alkylation reactions. This reaction type is crucial for the construction of carbon-carbon bonds and is widely utilized in the synthesis of natural products and biologically active compounds.