1140-69-8

Basic information

• Product Name: 1H-Pyrazole-3-carboxylic acid, 2,5-dihydro-5-oxo-2-phenyl-, methyl ester
• CAS NO: 1140-69-8
• Molecular Formula: C11H10N2O3
• Molecular Weight: 218.212
• Mol File: 1140-69-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazole-3-carboxylic acid, 2,5-dihydro-5-oxo-2-phenyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-3-carboxylic acid, 2,5-dihydro-5-oxo-2-phenyl-, methyl ester(1140-69-8)
• EPA Substance Registry System: 1H-Pyrazole-3-carboxylic acid, 2,5-dihydro-5-oxo-2-phenyl-, methyl ester(1140-69-8)

Safety Data

• Hazardous Substances Data: 1140-69-8(Hazardous Substances Data)

Usage

Type of compound

Methyl ester derivative of pyrazole-3-carboxylic acid

Contains

A phenyl group

Usage

Organic synthesis and medicinal chemistry

Purpose

Building block for the preparation of various pharmaceuticals and bioactive compounds

Biological activities

Potential anti-inflammatory, anticancer, and antimicrobial properties

Applications

Development of new drugs and agrochemicals

Upstream product

• 3950-18-3 3-hydroxy-1-phenyl-1H-pyrazole-5-carboxylic acid 
• 100-63-0 phenylhydrazine 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 464185-42-0 methyl 3-benzyloxy-1-phenyl-1H-pyrazole-5-carboxylate 

Downstream Products

• 464185-42-0 methyl 3-benzyloxy-1-phenyl-1H-pyrazole-5-carboxylate 
• 92576-30-2 methyl 3-methoxy-1-phenyl-1H-pyrazole-5-carboxylate 

Relevant articles and documents

CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF

Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.

1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY

A compound represented by the formula (1) wherein ring A is a ring optionally having 1 to 3 substituents; ring B is a 1,2-azole ring which may further have 1 to 3 substituents; Xa, Xb and Xc are the same or different and each is a bond, - O -, - S - and the like; Ya is a divalent aliphatic hydrocarbon residue having 1 to 20 carbon atoms; Yb and Yc are the same or different and each is a bond or a divalent aliphatic hydrocarbon residue having 1 to 20 carbon atoms; ring C is a monocyclic aromatic ring which may further have 1 to 3 substituents; and R represents -OR4 (R4 is hydrogen atom or optionally substituted hydrocarbon group) and the like, or a salt thereof or a prodrug thereof is useful as an agent for the prophylaxis or treatment of diabetes and the like.