114080-94-3

Basic information

• Product Name: Isoxazolo[5,4-c]pyridin-3-amine (9CI)
• Synonyms: Isoxazolo[5,4-c]pyridin-3-amine;Isoxazolo[5,4-c]pyridin-3-amine (9CI);Isoxazolo[5,4-c]pyridin-3-ylamine
• CAS NO: 114080-94-3
• Molecular Formula: C6H5N3O
• Molecular Weight: 135.1234
• Product Categories: organic building block;PYRIDINE
• Mol File: 114080-94-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 361.3°C at 760 mmHg
• Flash Point: 172.3°C
• Appearance: /
• Density: 1.421g/cm³
• Vapor Pressure: 2.1E-05mmHg at 25°C
• Refractive Index: 1.701
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: Isoxazolo[5,4-c]pyridin-3-amine (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Isoxazolo[5,4-c]pyridin-3-amine (9CI)(114080-94-3)
• EPA Substance Registry System: Isoxazolo[5,4-c]pyridin-3-amine (9CI)(114080-94-3)

Safety Data

• Hazardous Substances Data: 114080-94-3(Hazardous Substances Data)

Usage

General Description

Isoxazolo[5,4-c]pyridin-3-amine (9CI) is a chemical compound with the molecular formula C_7H_6N_4O. It is categorized under the class of isoxazoles, organic compounds containing a five-membered ring made up of one oxygen atom, one nitrogen atom, and three carbon atoms. The compound's three-dimensional molecular structure allows it to bind well with various biological receptors. It is primarily utilized in pharmaceutical research, serving as a building block in the development and synthesis of new potential drugs. The safety, environmental impact, and toxicity of the chemical are yet to be fully understood, and thus should be handled according to standard laboratory procedures.

InChI:InChI=1/C6H5N3O/c7-6-4-1-2-8-3-5(4)10-9-6/h1-3H,(H2,7,9)

Upstream product

• 113770-88-0 3-fluoro-4-pyridinecarbonitrile 
• 68325-15-5 3-chloro-isonicotinonitrile 
• 546-88-3 acetylhydroxamic acid 
• 6602-54-6 2-chloro-3-pyridinecarbonitrile 

Downstream Products

• 1229383-68-9 isoxazolo[5,4-c]pyridin-3-yl-carbamic acid phenyl ester 
• 1230019-43-8 4-[3-(4-chloro-phenoxy)-benzyl]-piperazine-1-carboxylic acid isoxazolo[5,4-c]pyridin-3-ylamide 

Relevant articles and documents

A high-yielding method for the preparation of isoxazolopyridin-3-amine derivatives

A highly efficient and green method has been developed for the rapid preparation of highly functionalized isoxazolopyridin-3-amine derivatives in excellent yields. This process has a broad substrate scope, is operationally simple, and generally requires no chromatographic purification. In addition, the process is scalable and significantly greener than current alternatives with a PMI of 18 and water as the reaction solvent.

SUBSTITUTED 3-AMINOISOXAZOLOPYRIDINES AS KCNQ2/3 MODULATORS

The invention relates to substituted 3-aminoisoxazolopyridines, to processes for their preparation, to medicaments containing these compounds and to the use of these compounds in the preparation of medicaments.

HETEROARYL-SUBSTITUTED UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE

Certain heteroaryl-substituted piperidinyl and piperazinyl urea compounds are described, which are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity, such as anxiety, pain, inflammation, sleep disorders, eating disorders, insulin resistance, diabetes, osteoporosis, and movement disorders (e.g., multiple sclerosis).