1141768-83-3

Basic information

• Product Name: γ-L-Glu-[(S)-4-amino-2-hydroxybutyryl]-neamine
• Synonyms: γ-L-Glu-[(S)-4-amino-2-hydroxybutyryl]-neamine
• CAS NO: 1141768-83-3
• Molecular Weight: 552.582
• Mol File: 1141768-83-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: γ-L-Glu-[(S)-4-amino-2-hydroxybutyryl]-neamine(CAS DataBase Reference)
• NIST Chemistry Reference: γ-L-Glu-[(S)-4-amino-2-hydroxybutyryl]-neamine(1141768-83-3)
• EPA Substance Registry System: γ-L-Glu-[(S)-4-amino-2-hydroxybutyryl]-neamine(1141768-83-3)

Safety Data

• Hazardous Substances Data: 1141768-83-3(Hazardous Substances Data)

Upstream product

• 1064665-41-3 γ-L-Glu-((S)-4-amino-2-hydroxybutyryl)-N-acetylcysteamine thioester 
• 3947-65-7 neomycin A 

Relevant articles and documents

Combined chemical-enzymatic assembly of aminoglycoside derivatives with N-1-AHB side chain

A series of unprotected pseudo-disaccharides and pseudo-trisaccharides of 2-deoxystreptamine-containing aminoglycosides have been selectively acylated at the N-1 position with the valuable (S)-4-amino-2-hydroxybutanoyl (AHB) pharmacophore by using the recombinant BtrH and BtrG enzymes from butirosin biosynthesis in combination with a synthetic acyl donor. The process was optimized by performing two enzymatic steps in a sequential manner without purification of the intermediate product.