114417-84-4 Usage
Description
NOJIRIMYCIN-1-SULFONIC ACID is a white crystalline solid that serves as an inhibitor for various glucosidases. It can be chemically modified to produce Nojirimycin through treatment with Basic Resin, which is a significant aspect of its chemical properties.
Uses
Used in Pharmaceutical Industry:
NOJIRIMYCIN-1-SULFONIC ACID is used as an enzyme inhibitor for its ability to inhibit several glucosidases. This property makes it a valuable compound in the development of drugs targeting specific glucosidase-related conditions.
Used in Chemical Synthesis:
NOJIRIMYCIN-1-SULFONIC ACID is used as a chemical intermediate for the synthesis of Nojirimycin, which is an important step in the production of various pharmaceutical compounds. The conversion process involves treatment with Basic Resin, highlighting its role in chemical synthesis and drug development.
Used in Research and Development:
As a glucosidase inhibitor, NOJIRIMYCIN-1-SULFONIC ACID is utilized in research and development for studying the function and role of glucosidases in various biological processes. This can lead to a better understanding of related diseases and the development of targeted therapies.
Used in Drug Design:
NOJIRIMYCIN-1-SULFONIC ACID is used as a structural component in the design of new drugs that target glucosidase enzymes. Its unique properties and ability to inhibit these enzymes make it a promising candidate for the development of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 114417-84-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,4,1 and 7 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 114417-84:
(8*1)+(7*1)+(6*4)+(5*4)+(4*1)+(3*7)+(2*8)+(1*4)=104
104 % 10 = 4
So 114417-84-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H13NO7S/c8-1-2-3(9)4(10)5(11)6(7-2)15(12,13)14/h2-11H,1H2,(H,12,13,14)/t2-,3-,4+,5-,6?/m1/s1
114417-84-4Relevant articles and documents
PRACTICAL SYNTHESIS OF NOJIRIMYCIN
Tsuda, Yoshisuke,Okuno, Yukihiro,Kanemitsu, Kimihiro
, p. 63 - 66 (1988)
The short step and efficient synthesis of nojirimycin (1) from commercially available 1,2-isopropylidene-D-glucofuranose (2) was described.Oxidation of 2 with (Bu3Sn)2O-Br2 followed by oximation, isomerization, and stereoselective reduction gave the 5-amino derivative of gluco-configuration (6a), which was converted to nojirimycin bisulfite adduct (8) in 50percent overall isolated yield.
SYNTHESIS OF (+)-GALACTOSTATIN
Aoyagi, Sakae,Fujimaki, Satoshi,Yamazaki, Naoki,Kibayashi, Chihiro
, p. 783 - 787 (2007/10/02)
The chiral synthesis of (+)-galactostatin (3), a new β-galactosidase inhibitor, has been achieved, in which the key step involved a diastereoselective epoxidation of the allylic alcohol (4) derived from L-tartaric acid.
