114438-75-4 Usage
Description
(2R)-2-bromo-Butanoic acid methyl ester is a chemical compound with the molecular formula C5H9BrO2. It is a methyl ester derivative of (2R)-2-bromo-butanoic acid, featuring a bromine atom and a carboxylic acid functional group. This colorless liquid with a characteristic odor is known for its ability to undergo nucleophilic substitution, making it useful in a variety of synthetic processes. It is important to handle it with care due to its potential irritant properties.
Uses
Used in Organic Synthesis:
(2R)-2-bromo-Butanoic acid methyl ester is used as a reagent in organic synthesis for its ability to undergo nucleophilic substitution, which is crucial in various synthetic processes.
Used in Chemical Reactions:
In the chemical industry, (2R)-2-bromo-Butanoic acid methyl ester is used as a reagent to facilitate specific chemical reactions, taking advantage of its unique bromine atom and carboxylic acid functional group.
Check Digit Verification of cas no
The CAS Registry Mumber 114438-75-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,4,3 and 8 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 114438-75:
(8*1)+(7*1)+(6*4)+(5*4)+(4*3)+(3*8)+(2*7)+(1*5)=114
114 % 10 = 4
So 114438-75-4 is a valid CAS Registry Number.
114438-75-4Relevant articles and documents
GC separation of enantiomers of alkyl esters of 2-bromo substituted carboxylic acids enantiomers on 6-tbdms-2,3-di-alkyl- β- And γ-cyclodextrin stationary phases
Spanik, Ivan,Kaceriakova, Darina,Krupcik, Jan,Armstrong, Daniel Wayne
, p. 279 - 285 (2014/06/09)
The gas chromatographic separation of enantiomers of 2-Br carboxylic acid derivatives was studied on four different 6-TBDMS-2,3-di-O-alkyl- β- and -γ-CD stationary phases. The differences in thermodynamic data {ΔH and -ΔS} for the 15 structurally related
Enantioselectivity of haloalkane dehalogenases and its modulation by surface loop engineering
Prokop, Zbynek,Sato, Yukari,Brezovsky, Jan,Mozga, Tomas,Chaloupkova, Radka,Koudelakova, Tana,Jerabek, Petr,Stepankova, Veronika,Natsume, Ryo,Van Leeuwen, Jan G. E.,Janssen, Dick B.,Florian, Jan,Nagata, Yuji,Senda, Toshiya,Damborsky, Jiri
supporting information; experimental part, p. 6111 - 6115 (2010/11/05)
In the loop: Engineering of the surface loop in haloalkane dehalogenases affects their enantiodiscrimination behavior. The temperature dependence of the enantioselectivity (lnE versus 1/T) of β-bromoalkanes by haloalkane dehalogenases is reversed (red data points) by deletion of the surface loop; the selectivity switches back when an additional single-point mutation is made. This behavior is not observed for -bromoesters.
