114438-79-8

Basic information

• Product Name: Hexanoic acid, 2-bromo-, methyl ester, (R)-
• CAS NO: 114438-79-8
• Molecular Formula: C7H13BrO2
• Molecular Weight: 209.083
• Mol File: 114438-79-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Hexanoic acid, 2-bromo-, methyl ester, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Hexanoic acid, 2-bromo-, methyl ester, (R)-(114438-79-8)
• EPA Substance Registry System: Hexanoic acid, 2-bromo-, methyl ester, (R)-(114438-79-8)

Safety Data

• Hazardous Substances Data: 114438-79-8(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 91423-84-6 (2S)-2-bromohexanoic acid 
• 616-05-7 2-bromohexanoic acid 
• 5445-19-2 methyl 2-bromohexanoate 
• 13894-63-8 methyl (E)-hex-2-enoate 
• 931382-07-9 C₇H₁₁BrO₂ 
• 186581-53-3 diazomethane 
• 931382-06-8 C₇H₁₁BrO₂ 

Relevant articles and documents

GC separation of enantiomers of alkyl esters of 2-bromo substituted carboxylic acids enantiomers on 6-tbdms-2,3-di-alkyl- β- And γ-cyclodextrin stationary phases

The gas chromatographic separation of enantiomers of 2-Br carboxylic acid derivatives was studied on four different 6-TBDMS-2,3-di-O-alkyl- β- and -γ-CD stationary phases. The differences in thermodynamic data {ΔH and -ΔS} for the 15 structurally related

Enantioselective synthesis of α-bromo acid derivatives and bromohydrins from tartrate derived bromoacetals

Bromination of the acetals 4 derived from aryl alkyl ketones, ArCOR, and (2R,3R)-tartaric acid results in bromoacetals 5 with 78-90% de. Hydrolysis of those compounds with Ar = 4-methoxyphenyl or 3-bromo-4-methoxyphenyl results, after recrystallisation, in α-bromoketones 8 with 66-98% ee which are shown to undergo the Baeyer-Villiger oxidation to α-bromoesters 9 with minimal racemisation, α-Bromoketone 8d is shown to undergo carbonyl reduction to threo-bromohydrin 15 with retention of stereochemistry.