1144505-43-0

Basic information

• Product Name: 5-(4-methoxyphenyl)-1-methylpyrrolidine-2,3-dione
• CAS NO: 1144505-43-0
• Molecular Weight: 219.24
• Mol File: 1144505-43-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(4-methoxyphenyl)-1-methylpyrrolidine-2,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-methoxyphenyl)-1-methylpyrrolidine-2,3-dione(1144505-43-0)
• EPA Substance Registry System: 5-(4-methoxyphenyl)-1-methylpyrrolidine-2,3-dione(1144505-43-0)

Safety Data

• Hazardous Substances Data: 1144505-43-0(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 904604-04-2 ethyl 4-hydroxy-2-(4-methoxyphenyl)-1-methyl-5-oxo-2,5-dihydro-1H-pyrrole-3-carboxylate 

Relevant articles and documents

Synthesis and bioactivity of some 2-oxo-5-aryl-3-hydrazone and 2-oxo-5-aryl-4-hydrazone pyrrolidine derivatives

2-Aryl-4,5-dioxopyrrolidine-3-carboxylate and 5-aryl-2,4-dioxopyrrolidine- 3-carboxylate derivatives were successfully synthesized via carbonyl-based multiple component reaction and Dieckmann cyclization, respectively. Successive functional group transformations which include decarboxylation and hydrazonation afforded 2-oxo-5-aryl-3-hydrazone and 2-oxo-5-aryl-4-hydrazone derivatives. Compound 3d exhibited activity against human histiocytic lymphoma (U937) and neuroblastoma (SH-SY5Y) cell lines while compound 6 showed neuroprotective ability from oxidative stress medium induced with H2O2.