114678-98-7Relevant articles and documents
Equilibria among Anions α-Hydroxy β-Diketones and α-Ketol Esters
Rubin, Mordecai B.,Inbar, Shai
, p. 3355 - 3358 (1988)
-
Molecular modeling based approach, synthesis, and cytotoxic activity of novel benzoin derivatives targeting phosphoinostide 3-kinase (PI3Kα)
Sabbah, Dima A.,Saada, Musaab,Khalaf, Reema Abu,Bardaweel, Sanaa,Sweidan, Kamal,Al-Qirim, Tariq,Al-Zughier, Amani,Halim, Heba Abdel,Sheikha, Ghassan Abu
supporting information, p. 3120 - 3124 (2015/07/08)
Abstract The oncogenic potential of phosphatidylinositol 3-kinase (PI3Kα) has made it an attractive target for anticancer drug design. In this work, we describe our efforts to optimize the lead PI3Kα inhibitor 2-hydroxy-1,2-diphenylethanone (benzoin). A s