1147-23-5 Usage
Description
5-Iodocytidine is a chemical compound that serves as an intermediate in the research of nucleic acids and nucleic acid-protein interactions. It is characterized by its white powder form.
Uses
Used in Research Applications:
5-Iodocytidine is used as a research intermediate for studying the interactions between nucleic acids and proteins. Its application is crucial in understanding the fundamental mechanisms of genetic information transfer and regulation within biological systems.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 5-Iodocytidine is utilized as a key component in the development of drugs targeting nucleic acid-related diseases. Its role in this industry is to facilitate the creation of novel therapeutics that can potentially treat various genetic disorders and conditions influenced by nucleic acid-protein interactions.
Used in Diagnostics:
5-Iodocytidine is also employed in the development of diagnostic tools and techniques that rely on the detection and analysis of nucleic acids. Its application in this field aids in the early identification and monitoring of diseases at the molecular level, contributing to more accurate and timely medical interventions.
Check Digit Verification of cas no
The CAS Registry Mumber 1147-23-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,1,4 and 7 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1147-23:
(6*1)+(5*1)+(4*4)+(3*7)+(2*2)+(1*3)=55
55 % 10 = 5
So 1147-23-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H12IN3O5/c10-3-1-13(9(17)12-7(3)11)8-6(16)5(15)4(2-14)18-8/h1,4-6,8,14-16H,2H2,(H2,11,12,17)/t4-,5-,6-,8-/m1/s1
1147-23-5Relevant articles and documents
A DNA-inspired synthetic ion channel based on G-C base pairing
Das, Rabindra Nath,Kumar, Y. Pavan,Schütte, Ole Mathis,Steinem, Claudia,Dash, Jyotirmayee
, p. 34 - 37 (2015)
A dinucleoside containing guanosine and cytidine at the end groups has been prepared using a modular one-pot azide-alkyne cycloaddition. Single channel analysis showed that this dinucleoside predominantly forms large channels with 2.9 nS conductance for the transport of potassium ions across a phospholipid bilayer. Transmission electron microscopy, atomic force microscopy, and circular dichroism spectroscopy studies reveal that this dinucleoside can spontaneously associate through Watson-Crick canonical H-bonding and π-π stacking to form stable supramolecular nanostructures. Most importantly, the ion channel activity of this G-C dinucleoside can be inhibited using the nucleobase cytosine.
Preparation method of novel nucleoside derivatives
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Paragraph 0015-0016; 0019-0020, (2017/08/29)
The invention aims at providing a synthetic method of fluorescent nucleoside derivatives obtained by a reaction with 4-substituted phenylacetylene and 5-iodocytidine as raw materials in the catalysis of palladium dichloride/CuI. The method is characterize
ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF
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Page/Page column 642, (2016/06/28)
The present disclosure provides alternative nucleosides, nucleotides, and nucleic acids, and methods of using them.
