114872-80-9 Usage
General Description
(R)-N-Acetyl-5-Fluoro-Trp-OMe is a chemical compound that belongs to the class of tryptophan derivatives. It is composed of an acetyl group, a fluoro group, and a tryptophan moiety. (R)-N-Acetyl-5-Fluoro-Trp-OMe has potential applications in medicinal chemistry, particularly in the development of new pharmaceuticals and biologically active molecules. Its structure and properties make it a valuable tool for studying the structure-activity relationships of tryptophan-containing compounds, as well as for use in research and drug development efforts. Additionally, (R)-N-Acetyl-5-Fluoro-Trp-OMe may have a range of biological effects that could be exploited for therapeutic purposes, such as in the treatment of neurological disorders, cancer, and infectious diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 114872-80-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,8,7 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 114872-80:
(8*1)+(7*1)+(6*4)+(5*8)+(4*7)+(3*2)+(2*8)+(1*0)=129
129 % 10 = 9
So 114872-80-9 is a valid CAS Registry Number.
InChI:InChI=1/C14H15FN2O3/c1-8(18)17-13(14(19)20-2)5-9-7-16-12-4-3-10(15)6-11(9)12/h3-4,6-7,13,16H,5H2,1-2H3,(H,17,18)/t13-/m1/s1
114872-80-9Relevant articles and documents
The facile synthesis of a series of tryptophan derivatives
Blaser, Georg,Sanderson, John M.,Batsanov, Andrei S.,Howard, Judith A.K.
, p. 2795 - 2798 (2008/09/19)
This study reports a facile method for the synthesis of a variety of 5- and 6-substituted tryptophan derivatives that are difficult to prepare using alternative enzymatic approaches. Acylation of an activated amino acid, derived from serine in situ, is coupled with an enzymatic resolution step to furnish enantiopure analogues bearing a range of electron withdrawing and releasing substituents. Isolation of a dehydroalanine derivative as a by-product from some reactions provides some insights into the likely mechanism of the reaction.
