114936-37-7

Basic information

• Product Name: 2-(3-amino-1-methyl-4-pyrazolyl)-5-phenyl-1,3,4-oxadiazole
• CAS NO: 114936-37-7
• Molecular Weight: 241.252
• Mol File: 114936-37-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(3-amino-1-methyl-4-pyrazolyl)-5-phenyl-1,3,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-amino-1-methyl-4-pyrazolyl)-5-phenyl-1,3,4-oxadiazole(114936-37-7)
• EPA Substance Registry System: 2-(3-amino-1-methyl-4-pyrazolyl)-5-phenyl-1,3,4-oxadiazole(114936-37-7)

Safety Data

• Hazardous Substances Data: 114936-37-7(Hazardous Substances Data)

Upstream product

• 1663-61-2 triethoxymethylbenzene 
• 114936-30-0 β-(ethoxybenzylidene) 3-amino-1-methylpyrazole-4-carboxhydrazide 
• 114936-29-7 3-amino-1-methyl-1H-pyrazole-4-carboxhydrazide 

Relevant articles and documents

Synthesis of 5-amino-4,5-dihydropyrazolo [3,4-d] pyrimidin-4-ones and related isomeric systems. Part II. Ring closure reactions

Treatment of ethyl (heteroalkylidene)aminopyrazole-4-carboxylates with hydrazine hydrate generally provides a ready synthetic route to 5-amino-4, 5-dihydropyrazolo [3,4-d] pyrimidin-4-ones, although ethyl 5-[(dimethylamino) alkylidene]aminopyrazole-4-carboxylates are unreactive. On the other hand, reactions between aminopyrazole-4-carboxhydrazides and orthoesters or amide acetal are more versatile : we observed formation of isomeric 2-pyrazolyl-1,3,4-oxadiazoles, as major compounds, either from triethyl orthoacetate and 1-methyl-5-aminopyrazole-4-carboxhydrazide or from dimethylacetamide dimethyl acetal and various heterocyclic precursors. The ring closure mechanism is discussed.