1150114-52-5 Usage
Description
2-Fluoro-5-hydroxyphenylboronic acid is an organic compound that features a boron atom bonded to a phenyl ring with a fluorine atom at the 2nd position and a hydroxyl group at the 5th position. This molecule is known for its unique chemical properties and reactivity, making it a valuable building block in the synthesis of various organic compounds and pharmaceuticals.
Uses
Used in Suzuki Reaction:
2-Fluoro-5-hydroxyphenylboronic acid is used as a key intermediate in the Suzuki reaction, a widely employed cross-coupling reaction in organic chemistry. This reaction allows for the formation of carbon-carbon bonds, which are crucial in the synthesis of complex organic molecules and pharmaceuticals. The unique properties of 2-Fluoro-5-hydroxyphenylboronic acid make it a valuable component in this process, enabling the creation of a diverse range of molecular structures.
Used in Pharmaceutical Industry:
2-Fluoro-5-hydroxyphenylboronic acid is used as a building block for the preparation of pyrrolopyrimidine derivatives, which are known as IGF-1R inhibitors. These inhibitors play a significant role in the development of targeted cancer therapies, as they can help regulate the activity of the insulin-like growth factor 1 receptor (IGF-1R), a protein that is often overexpressed in various types of cancer. By inhibiting IGF-1R, these pyrrolopyrimidine derivatives can potentially slow down or halt the growth and progression of cancer cells, making them a promising avenue for cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 1150114-52-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,0,1,1 and 4 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1150114-52:
(9*1)+(8*1)+(7*5)+(6*0)+(5*1)+(4*1)+(3*4)+(2*5)+(1*2)=85
85 % 10 = 5
So 1150114-52-5 is a valid CAS Registry Number.
