115134-32-2

Basic information

• Product Name: L-Alanine, N-(diphenylmethylene)-, methyl ester
• CAS NO: 115134-32-2
• Molecular Formula: C17H17NO2
• Molecular Weight: 267.327
• Mol File: 115134-32-2.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: L-Alanine, N-(diphenylmethylene)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Alanine, N-(diphenylmethylene)-, methyl ester(115134-32-2)
• EPA Substance Registry System: L-Alanine, N-(diphenylmethylene)-, methyl ester(115134-32-2)

Safety Data

• Hazardous Substances Data: 115134-32-2(Hazardous Substances Data)

Upstream product

• 1013-88-3 Benzophenone imine 
• 2491-20-5 L-alanine methyl ester hydrochloride 
• 13515-97-4 methyl 2-aminopropanoate monohydrochloride 
• 119-61-9 benzophenone 
• 14316-06-4 D-alanine methyl ester hydrochloride 
• 81167-39-7 methyl N-(diphenylmethylene)glycinate 
• 115149-86-5 Sulfuric acid (3aR,5R,6S,6aR)-5-((2S,4R)-2-tert-butyl-2-methyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester methyl ester 
• 115149-79-6 Sulfuric acid (3aR,5R,6S,6aR)-5-ethyl-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-6-yl ester methyl ester 
• 7625-53-8 rac-Ala-OMe 

Downstream Products

• 867266-89-5 (E)-(2S,3R)-2-(Benzhydrylidene-amino)-2,3-dimethyl-5-phenyl-pent-4-enoic acid methyl ester 
• 868665-17-2 methyl 2-[(diphenylmethylene)amino]-2-methyl-3-pyridin-4-ylpropanoate 
• 1308287-14-0 C₁₇⁽¹¹⁾CH₁₉NO₂ 

Relevant articles and documents

Investigation into the enantioselective protonation of enolate Schiff bases with (R)-pantolactone

The effect of several factors on the enantioselective protonation of the enolates of α-amino acid derivatives with (R)-pantolactone were studied. The highest stereoselectivity (74-76% e.e.) was generally observed by associating lithium chloride with LHMDS

CYCLIZED SULFAMOYLARYLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B

Inhibitors of HBV replication of Formula (I-A), including stereochemically isomeric forms, and salts, hydrates, solvates thereof, wherein Ra to Rd, and R1 to R8 have the meaning as defined herein. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use, alone or in combination with other HBV inhibitors, in HBV therapy.

A convenient method for the enantiomeric separation of α-amino acid esters as benzophenone imine schiff base derivatives

A convenient liquid chromatographic method for the separation of α-amino acid esters as benzophenone Schiff base derivatives on coated chiral stationary phases (CSPs) (Chiralcel OD-H, Chiralcel OD, Chiralpak AD-H, Chiralpak AD, and Chiralpak AS) or covalently immobilized CSPs (Chiralpak IA, Chiralpak IB, and Chiralpak IC) derived from polysaccharide derivatives is described. Benzophenone imine derivatives of α-amino acid esters were readily prepared by stirring benzophenone imine and the hydrochloride salts of α-amino acid esters in 2-propanol. The chromatographic separations were conducted at a flow rate 1.0 mL/min and a detection wavelength of 254 nm; 0.5% 2-propanol/hexane (v/v) was used on CSPs. In general, the resolution of Chiralpak IC was superior to those of the other CSPs. In addition, the resolutions of other arylimine derivatives of α-amino acid esters and the effects of different mobile phases on the enantiomeric separation of α-amino acid esters as benzophenone imine derivatives on Chiralpak IC were investigated.