1154912-76-1

Basic information

• Product Name: N-(3,4-dimethoxybenzyl)-1H-pyrrole
• Synonyms: N-(3,4-dimethoxybenzyl)-1H-pyrrole
• CAS NO: 1154912-76-1
• Molecular Weight: 217.268
• Mol File: 1154912-76-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(3,4-dimethoxybenzyl)-1H-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3,4-dimethoxybenzyl)-1H-pyrrole(1154912-76-1)
• EPA Substance Registry System: N-(3,4-dimethoxybenzyl)-1H-pyrrole(1154912-76-1)

Safety Data

• Hazardous Substances Data: 1154912-76-1(Hazardous Substances Data)

Upstream product

• 109-97-7 pyrrole 
• 7306-46-9 4-chloromethyl-1,2-dimethoxy-benzene 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 51-35-4 4R-4-hydroxyproline 

Relevant articles and documents

An enantioselective synthesis of α-alkylated pyrroles: Via cooperative isothiourea/palladium catalysis

Herein we describe the direct enantioselective Lewis base/Pd catalysed α-allylation of pyrrole acetic acid esters. This provides high isolated yields of highly enantioenriched products and exhibits broad reaction scope with respect to both reaction partners. The products can be readily elaborated in a manner which points towards potential applications in target directed synthesis.

Synthesis of N-alkyl pyrroles via decarboxylation/dehydration in neutral ionic liquid under catalyst-free conditions

A general route to N-alkyl pyrroles by reacting aromatic, heteroaromatic or aliphatic aldehydes with 4-hydroxyproline in ionic liquid under neutral condition was developed. The ionic liquid can be readily recovered and reused for up to 5 reaction cycles without any effect on the yield of the product formed. The utility of the protocol for the one-pot synthesis of 9H-benzo[e]pyrrolo[2,1-b][1,3]oxazines is also presented.