115514-75-5Relevant articles and documents
Tetrahydroisoquinolines as dopaminergic ligands: 1-Butyl-7-chloro-6-hydroxy-tetrahydroisoquinoline, a new compound with antidepressant-like activity in mice
Berenguer, Inmaculada,Aouad, Noureddine El,Andujar, Sebastian,Romero, Vanessa,Suvire, Fernando,Freret, Thomas,Bermejo, Almudena,Ivorra, Maria Dolores,Enriz, Ricardo D.,Boulouard, Michel,Cabedo, Nuria,Cortes, Diego
experimental part, p. 4968 - 4980 (2009/12/04)
Three series of 1-substituted-7-chloro-6-hydroxy-tetrahydroisoquinolines (1-butyl-, 1-phenyl- and 1-benzyl derivatives) were prepared to explore the influence of each of these groups at the 1-position on the affinity for dopamine receptors. All the compou