1155555-12-6 Usage
Ketone derivative
Presence of a carbonyl group (C=O)
The compound has a carbonyl group (C=O) which is a characteristic feature of ketone derivatives.
Diazepan ring
A five-membered ring with two nitrogen atoms
The structure contains a diazepan ring, which is a five-membered ring with two nitrogen atoms, contributing to its potential pharmacological properties.
Indole moiety
Aromatic bicyclic system with a nitrogen atom
The compound features an indole moiety, an aromatic bicyclic system with a nitrogen atom, which is commonly found in natural products and pharmaceuticals.
Potential pharmacological properties
Anticonvulsant, antidepressant, anxiolytic, and sedative effects
1H-indol-2-yl-(4-methyl-1,4-diazepan-1-yl)methanone may exhibit various pharmacological properties, such as anticonvulsant or antidepressant effects due to the diazepan ring and indole moiety. The diazepan ring suggests potential anxiolytic and sedative characteristics.
Application in medicinal chemistry
Potential uses and effects
The compound has potential applications in medicinal chemistry, as it may exhibit various pharmacological properties and interact with biological systems.
Further research and testing needed
To fully understand its potential uses and effects
More research and testing are required to determine the exact potential uses and effects of 1H-indol-2-yl-(4-methyl-1,4-diazepan-1-yl)methanone in the field of medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1155555-12-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,5,5,5,5 and 5 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1155555-12:
(9*1)+(8*1)+(7*5)+(6*5)+(5*5)+(4*5)+(3*5)+(2*1)+(1*2)=146
146 % 10 = 6
So 1155555-12-6 is a valid CAS Registry Number.
1155555-12-6Relevant articles and documents
Detailed structure-activity relationship of indolecarboxamides as H 4 receptor ligands
Engelhardt, Harald,De Esch, Iwan J.P.,Kuhn, Daniel,Smits, Rogier A.,Zuiderveld, Obbe P.,Dobler, Julia,Mayer, Moriz,Lips, Sebastian,Arnhof, Heribert,Scharn, Dirk,Haaksma, Eric E.J.,Leurs, Rob
experimental part, p. 660 - 668 (2012/09/07)
A series of 76 derivatives of the indolecarboxamide 1 were synthesized, which allows a detailed SAR investigation of this well known scaffold. The data enable the definition of a predictive QSAR model which identifies several compounds with an activity comparable to 1. A selection of these new H 4R antagonists was synthesized and a comparison of predicted and measured values demonstrates the robustness of the model (47-55). In addition to the H4-receptor activity general CMC and DMPK properties were investigated. Some of the new analogs are not only excellently soluble, but display a significantly increased half-life in mouse liver microsomes as well. These properties qualify these compounds as a possible new standard for future in vivo studies (e.g 51, 52 and 55). Moreover, the current studies also provide valuable information on the potential receptor ligand interactions between the indolcarboxamides and the H4R protein.
